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Saralasin

Known as: Angiotensin II, Sarcosyl(1)-Alanine(8)-, 1 Sar 8 Ala Angiotensin II, Sar-Arg-Val-Tyr-Val-His-Pro-Ala 
An octapeptide analog of angiotensin II (bovine) with amino acids 1 and 8 replaced with sarcosine and alanine, respectively. It is a highly specific… Expand
National Institutes of Health

Papers overview

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Review
2001
Review
2001
In the 1970s, a series of observations demonstrated that angiotensin II has deleterious effects on the heart and kidney and that… Expand
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Highly Cited
1997
Highly Cited
1997
To investigate potential interactions between angiotensin II (AII) and the insulin signaling system in the vasculature, insulin… Expand
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Highly Cited
1994
Highly Cited
1994
Angiotensin II (Ang II) has been implicated in the development of progressive glomerulosclerosis, but the precise mechanism of… Expand
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Highly Cited
1990
Highly Cited
1990
Specific binding sites for angiotensin II were identified in the rabbit adrenal gland and uterus and in the rat liver and were… Expand
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Highly Cited
1989
Highly Cited
1989
Recently, angiotensin II (Ang II) has been shown to cause hypertrophy of cultured quiescent rat aortic smooth muscle (RASM) cells… Expand
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Highly Cited
1977
Highly Cited
1977
Laser light scattered from tissue in vivo is broadened in line width as a result of the Doppler shift produced by moving red… Expand
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Highly Cited
1977
Highly Cited
1977
3H] and mounted for supervision and isometric tension recording. The superfusate was collected for estimation of total… Expand
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Highly Cited
1976
Highly Cited
1976
The role of a transmembrane calcium influx in hypoxic pulmonary vasoconstriction was studied in isolated, blood perfused, rat… Expand
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Highly Cited
1975
Highly Cited
1975
The possibility has been explored of using a specific angiotensin ii antagonist, saralasin (P-113, 1-sar-8-ala-angiotensin ii) to… Expand
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Highly Cited
1971
Highly Cited
1971
Experiments with rabbit aortic strips and pithed rats indicated that 1-Sar-8-Ala-angiotensin II (Sar-Arg-Val-Tyr-Val-His-Pro-Ala… Expand
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