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SWAP70 gene

Known as: KIAA0640, SWAP70, SWAP-70 
National Institutes of Health

Papers overview

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2017
2017
SWAP70 is a universal GEF-like adaptor for tethering actin to phagosomes
ABSTRACT We recently identified a key role for SWAP70 as the tethering factor stabilizing F-actin filaments on the surface of… 
2011
2011
Fine tuning of IRF‐4 expression by SWAP‐70 controls the initiation of plasma cell development
The generation of plasma cells (PCs) is key for proper humoral immune responses. The transcription factors IRF‐4 and BLIMP‐1 (B… 
2009
2009
The Guanine Nucleotide Exchange Factor SWAP-70 Modulates the Migration and Invasiveness of Human Malignant Glioma Cells 1 , 2
The malignant glioma is the most common primary human brain tumor. Its tendency to invade away from the primary tumor mass is… 
2008
2008
SWAP-70 deficiency causes high-affinity plasma cell generation despite impaired germinal center formation.
Germinal centers (GCs) are lymphoid tissue structures central to the generation of long-lived, high-affinity, antibody-forming B… 
2007
2007
Expression and Localization of SWAP-70 in Human Fetomaternal Interface and Placenta During Tubal Pregnancy and Normal Placentation
SWAP-70 has been demonstrated as a multiple functional signaling protein involved in formation of membrane ruffling induced by… 
2007
2007
SWAP-70 is required for oncogenic transformation by v-Src in mouse embryo fibroblasts.
2006
2006
Expression of SWAP-70 in the uterus and feto-maternal interface during embryonic implantation and pregnancy in the rhesus monkey (Macaca mulatta)
SWAP-70 is a unique signaling protein involved in multiple processes including lymphatic cell activation, migration, adhesion… 
2004
2004
Expression of the Diffuse B-cell Lymphoma Family Molecule SWAP-70 in Human B-cell Neoplasms: Immunohistochemical Study of 86 Cases
SWAP-70 is a recently discovered member of the Dbl (diffuse B-cell lymphoma) family of signal transduction molecules that is… 
2001
2001
Analysis of SWAP-70 as a candidate gene for non-X-linked hyper IgM syndrome and common variable immunodeficiency.
SWAP-70 is a recently identified protein that functions as the only B cell-specific component of an isotype switch recombination… 
Highly Cited
1999
Highly Cited
1999
Cellular, intracellular, and developmental expression patterns of murine SWAP‐70
SWAP‐70 is part of a protein complex that catalyzes cell‐free DNA recombination between immunoglobulin heavy chain gene switch… 
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