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SUPT16H gene

Known as: SPT16 homolog, facilitates chromatin remodeling subunit, CDC68, SUPPRESSOR OF TY 16, S. CEREVISIAE, HOMOLOG OF 
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Integrated molecular mechanism directing nucleosome reorganization by human FACT
Facilitates chromatin transcription (FACT) plays essential roles in chromatin remodeling during DNA transcription, replication… 
2015
2015
FACT Proteins, SUPT16H and SSRP1, Are Transcriptional Suppressors of HIV-1 and HTLV-1 That Facilitate Viral Latency*
Background: FACT proteins SUPT16H and SSRP1 are identified as host factors that restrict HIV-1 replication. Results: Biochemical… 
Highly Cited
2010
Highly Cited
2010
Ubiquitylation of FACT by the cullin-E3 ligase Rtt101 connects FACT to DNA replication.
FACT plays important roles in both gene transcription and DNA replication. However, how this protein complex is targeted to these… 
Highly Cited
2001
Highly Cited
2001
A Bipartite Yeast SSRP1 Analog Comprised of Pob3 and Nhp6 Proteins Modulates Transcription
ABSTRACT The FACT complex of vertebrate cells, comprising the Cdc68 (Spt16) and SSRP1 proteins, facilitates transcription… 
Highly Cited
1998
Highly Cited
1998
Characterization of the CP Complex, an Abundant Dimer of Cdc68 and Pob3 Proteins That Regulates Yeast Transcriptional Activation and Chromatin Repression*
The Cdc68 protein of the yeastSaccharomyces cerevisiae is an essential nuclear protein that has been shown to be necessary for… 
Highly Cited
1997
Highly Cited
1997
The Saccharomyces cerevisiae DNA polymerase alpha catalytic subunit interacts with Cdc68/Spt16 and with Pob3, a protein similar to an HMG1-like protein
We have used DNA polymerase alpha affinity chromatography to identify factors involved in eukaryotic DNA replication in the yeast… 
1994
1994
Differential effects of Cdc68 on cell cycle-regulated promoters in Saccharomyces cerevisiae
Swi4 and Swi6 form a complex which is required for Start-dependent activation of HO and for high-level expression of G1 cyclin… 
Highly Cited
1991
Highly Cited
1991
CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus
The cell cycle of the budding yeast Saccharomyces cerevisiae has been investigated through the study of conditional cdc mutations… 
Highly Cited
1991
Highly Cited
1991
Mutations in SPT16/CDC68 suppress cis- and trans-acting mutations that affect promoter function in Saccharomyces cerevisiae.
SPT16 was previously identified as a high-copy-number suppressor of delta insertion mutations in the 5' regions of the HIS4 and… 
Highly Cited
1990
Highly Cited
1990
Size selection identifies new genes that regulate Saccharomyces cerevisiae cell proliferation.
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