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STK17B gene

Known as: serine/threonine kinase 17b, death-associated protein kinase-related 2, STK17B 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
Discovery of indirubin derivatives as new class of DRAK2 inhibitors from high throughput screening.
2015
2015
Drak2 Does Not Regulate TGF-β Signaling in T Cells
Drak2 is a serine/threonine kinase expressed highest in T cells and B cells. Drak2-/- mice are resistant to autoimmunity in mouse… 
2012
2012
Loss of DRAK2 Signaling Enhances Allogeneic Transplant Survival by Limiting Effector and Memory T Cell Responses
Here, we demonstrate that loss of DRAK2 signaling significantly promotes the acceptance of allogeneic engraftment in two separate… 
2012
2012
Loss of DRAK2 signaling enhances allogeneic transplant survival by altering effector T cell responses and memory generation (126.24)
Drak2 is a serine threonine kinase that has previously been shown to negatively regulate activation of T cells through the T… 
Review
2012
Review
2012
Peer Reviewed Title: DRAK2 Participates in a Negative Feedback Loop to Control TGF-β/Smads Signaling by Binding to Type I TGF-β Receptor
2007
2007
Anti-viral effector T cell responses and trafficking are not dependent upon DRAK2 signaling following viral infection of the central nervous system
The signaling events involved in T cell trafficking into the central nervous system (CNS) following viral infection are not fully… 
2007
2007
DRAK2 regulates memory T cell responses following murine coronavirus infection
The contribution of DRAK2 [death-associated protein kinase (DAPK)-related apoptosis-inducing kinase 2] to anti-viral memory T… 
2007
2007
A critical role for DRAK2 in the germinal center reaction and the antibody response (84.1)
DRAK2 (DAP-related apoptotic kinase-2) protein is a DAP family member. DRAK2 is highly expressed in B and T lymphocytes and it… 
2005
2005
T-cell signalling: DRAK2 puts the brakes on T-cell responses
and produced more cytokine in response to TCR stimulation than wild-type T cells. Furthermore, whereas crosslinking of both CD3… 
Review
2001
Review
2001
A serine/threonine kinase which causes apoptosis-like cell death interacts with a calcineurin B-like protein capable of binding Na(+)/H(+) exchanger.
We surveyed proteins capable of binding to the cytoplasmic domain of Na(+)/H(+) exchanger (NHE)1 in a rat brain cDNA library with… 
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