STAT5b Transcription Factor
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Classical acute promyelocytic leukemia (APL) cases are associated with the promyelocytic leukemia-retinoic acid receptor α (PML… Expand BACKGROUND
The most frequent monogenic causes of growth hormone insensitivity (GHI) include defects in genes encoding the GH… Expand Determining the underlying cause of persistent eosinophilia is important for effective clinical management but remains a… Expand Lymphomas arising from NK or γδ-T cells are very aggressive diseases and little is known regarding their pathogenesis. Here we… Expand Cytokine-activated STAT proteins dimerize and bind to high-affinity motifs, and N-terminal domain-mediated oligomerization of… Expand Background: Stat5 transcription factors regulate genes required for cell growth, survival, and differentiation. Results: A novel… Expand T(15;17) is the most common chromosomal aberration in patients with acute promyelocytic leukemia (APL), leading to the formation… Expand A generalized increase in liver protein tyrosine nitration (3'-nitrotyrosine, 3'-NT) occurs after GH injection in a time frame… Expand Signal transducer and activator of transcription (STAT) 5b-retinoic acid receptor (RAR) alpha is the fifth fusion protein… Expand ABSTRACT The lactogenic hormones, i.e., prolactin and glucocorticoids, act in concert to stimulate transcription factors… Expand