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STAT5b Transcription Factor

Known as: Transcription Factor, STAT5b, Signal Transducer and Activator of Transcription 5B, STAT5b Protein 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

STAT5 Transcription Factor
STAT5B gene

Narrower (1)

STAT5B protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2019
Review
2019
Acute promyelocytic leukemia and variant fusion proteins: PLZF-RARα fusion protein at a glance.
Classical acute promyelocytic leukemia (APL) cases are associated with the promyelocytic leukemia-retinoic acid receptor α (PML… Expand
2019
2019
A novel heterozygous STAT5B variant in a patient with short stature and partial growth hormone insensitivity (GHI).
BACKGROUND The most frequent monogenic causes of growth hormone insensitivity (GHI) include defects in genes encoding the GH… Expand
2018
2018
Recurrent activating STAT5B N642H mutation in myeloid neoplasms with eosinophilia
Determining the underlying cause of persistent eosinophilia is important for effective clinical management but remains a… Expand
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Highly Cited
2015
Highly Cited
2015
Activating mutations of STAT5B and STAT3 in lymphomas derived from γδ-T or NK cells.
Lymphomas arising from NK or γδ-T cells are very aggressive diseases and little is known regarding their pathogenesis. Here we… Expand
Highly Cited
2012
Highly Cited
2012
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
Cytokine-activated STAT proteins dimerize and bind to high-affinity motifs, and N-terminal domain-mediated oligomerization of… Expand
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2012
2012
Signal Transducer and Activator of Transcription 5b (Stat5b) Serine 193 Is a Novel Cytokine-induced Phospho-regulatory Site That Is Constitutively Activated in Primary Hematopoietic Malignancies*
Background: Stat5 transcription factors regulate genes required for cell growth, survival, and differentiation. Results: A novel… Expand
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2011
2011
Identification of the STAT5B‐RARα fusion transcript in an acute promyelocytic leukemia patient without FLT3, NPM1, c‐Kit and C/EBPα mutation
T(15;17) is the most common chromosomal aberration in patients with acute promyelocytic leukemia (APL), leading to the formation… Expand
2007
2007
Growth hormone (GH)-associated nitration of Janus kinase-2 at the 1007Y-1008Y epitope impedes phosphorylation at this site: mechanism for and impact of a GH, AKT, and nitric oxide synthase axis on GH…
A generalized increase in liver protein tyrosine nitration (3'-nitrotyrosine, 3'-NT) occurs after GH injection in a time frame… Expand
Highly Cited
2002
Highly Cited
2002
Interactions of STAT5b-RARalpha, a novel acute promyelocytic leukemia fusion protein, with retinoic acid receptor and STAT3 signaling pathways.
Signal transducer and activator of transcription (STAT) 5b-retinoic acid receptor (RAR) alpha is the fifth fusion protein… Expand
Highly Cited
1998
Highly Cited
1998
Characterization of Stat5a and Stat5b Homodimers and Heterodimers and Their Association with the Glucocortiocoid Receptor in Mammary Cells
ABSTRACT The lactogenic hormones, i.e., prolactin and glucocorticoids, act in concert to stimulate transcription factors… Expand
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