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STA 5326
Known as:
STA-5326
, STA5326
National Institutes of Health
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Related topics
Related topics
2 relations
Broader (2)
Apilimod
apilimod mesylate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
IL-23R is Epigenetically Regulated and Modulated by Chemotherapy in Non-Small Cell Lung Cancer
A. Baird
,
É. Dockry
,
+4 authors
S. Gray
Frontiers in Oncology
2013
Corpus ID: 22718161
The Interleukin-23 (IL-23)/IL-23R signaling axis is an important inflammatory pathway, involved in the stimulation and regulation…
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Review
2011
Review
2011
New Interleukin-23 Pathway Inhibitors in Dermatology
M. Kurzeja
,
L. Rudnicka
,
M. Olszewska
American Journal of Clinical Dermatology
2011
Corpus ID: 34327142
Interleukin (IL)-23 is an important regulator of T helper-17 lymphocytes, which influence the cutaneous immune system by…
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Review
2010
Review
2010
[Therapeutic effect of the low molecular weight inhibitor of the NF-kappaB signaling pathway on experimental autoimmune uveoretinitis].
H. Keino
Nippon Ganka Gakkai zasshi
2010
Corpus ID: 25554608
The nuclear factor-kappaB (NF-kappaB) proteins are a family of ubiquitously expressed transcriptional proteins in most immune and…
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Highly Cited
2010
Highly Cited
2010
Randomized, double‐blind, placebo‐controlled trial of the oral interleukin‐12/23 inhibitor apilimod mesylate for treatment of active Crohn's disease
B. Sands
,
E. Jacobson
,
+4 authors
S. Greenbloom
Inflammatory Bowel Diseases
2010
Corpus ID: 26012456
Background: Interleukin‐12 (IL‐12) and interleukin‐23 (IL‐23) are inflammatory cytokines linked to the Th‐1 and Th‐17 phenotypes…
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2008
2008
Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis
H. Keino
,
Takayo Watanabe
,
Yasuhiko Sato
,
M. Niikura
,
Y. Wada
,
A. Okada
Arthritis Research & Therapy
2008
Corpus ID: 13633111
IntroductionThe purpose of this study was to determine if oral administration of the interleukin (IL) 12/IL-23 inhibitor, STA…
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2008
2008
Therapeutic Effect of the IL-12/IL-23 Inhibitor STA5326 in Experimental Autoimmune Uveoretinitis
H. Keino
,
M. Niikura
,
Y. Wada
,
A. Okada
2008
Corpus ID: 83397812
Highly Cited
2007
Highly Cited
2007
Selective abrogation of Th1 response by STA-5326, a potent IL-12/IL-23 inhibitor.
Y. Wada
,
Rongzhen Lu
,
+9 authors
M. Ono
Blood
2007
Corpus ID: 10282384
The interleukin-12 (IL-12) cytokine induces the differentiation of naive T cells to the T helper cell type 1 (Th1) phenotype and…
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2006
2006
STA5326 is a well-tolerated and effective treatment for active Crohn's disease
Nature Clinical Practice Gastroenterology…
2006
Corpus ID: 41530520
An Australian team has shown that fecal levels of S100A12—a calcium-binding protein found at high concentrations in the serum of…
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Highly Cited
2006
Highly Cited
2006
A phase 1/2A Trial of STA 5326, an oral interleukin‐12/23 inhibitor, in patients with active moderate to severe Crohn's disease
R. Burakoff
,
C. Barish
,
+11 authors
R. Bleday
Inflammatory Bowel Diseases
2006
Corpus ID: 25913767
Background: Intestinal inflammation associated with Crohn's disease is characterized by a type 1 helper T cell response and…
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