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SSX2 Protein

Known as: Synovial Sarcoma, X Breakpoint 2, SSX2, Protein SSX2 
Protein SSX2 (188 aa, ~22 kDa) is encoded by the human SSX2 and SSX2B genes. This protein may play a role in the modulation of transcription.
National Institutes of Health

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3 relations
Cell NucleusGenes, RegulatorSSX2 gene

Papers overview

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Highly Cited
2012
Highly Cited
2012
Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT–SSX2
Cell identity is determined by its gene expression programs. The ability of a cell to change its identity and produce cell types… 
2007
2007
Implicacion pronostica del estudio molecular del ganglio centinela en los pacientes con melanoma
INTRODUCCION: En la actualidad, se acepta que el procedimiento diagnostico mas preciso del estado patologico de los ganglios… 
2006
2006
Chronic myeloid leukemia cells express tumor-associated antigens eliciting specific CD8+ T-cell responses and are lacking costimulatory molecules.
2004
2004
[Expression of multiple cancer-testis antigen genes in non-small cell lung cancer treated by chemotherapy prior surgery].
OBJECTIVE To investigate the possibility of utilizing cancer-testi (CT) antigens as targets for immunotherapy of non-small cell… 
Highly Cited
2002
Highly Cited
2002
Proteasome-Assisted Identification of a SSX-2-Derived Epitope Recognized by Tumor-Reactive CTL Infiltrating Metastatic Melanoma1
The tumor Ag SSX-2 (HOM-MEL-40) was found by serological identification of Ags by recombinant expression cloning and was shown to… 
2001
2001
Expression patterns of cancer testis antigens in testicular germ cell tumors and adjacent testicular tissue.
Highly Cited
1998
Highly Cited
1998
Identification of a meiosis-specific protein as a member of the class of cancer/testis antigens.
Little is known about the function of human cancer/testis antigens (CTAs), such as MAGE, BAGE, GAGE, HOM-MEL-40, and NY-ESO-1… 
Highly Cited
1998
Highly Cited
1998
Expression of SSX genes in human tumors
The HOM‐MEL‐40 antigen which is encoded by the SSX‐2 gene was originally detected as a tumor antigen recognized by autologous IgG… 
Highly Cited
1997
Highly Cited
1997
SSX: A multigene family with several members transcribed in normal testis and human cancer
Analysis of t(X;18) translocation in synovial sarcoma had previously led to the definition of the SSX2 gene, the fusion partner… 
Highly Cited
1996
Highly Cited
1996
The SSX-2 gene, which is involved in the t(X;18) translocation of synovial sarcomas, codes for the human tumor antigen HOM-MEL-40.
Using autologous serum for the serological analysis of recombinantly expressed clones (SEREX) from a cDNA derived from a human… 
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