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SSR 149415

Known as: SSR-149415, SSR149415 
National Institutes of Health

Papers overview

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2017
2017
Arginine Vasopressin Alters Both Spontaneous and Phase-Locked Synaptic Inputs to Airway Vagal Preganglionic Neuron via Activation of V1a Receptor: Insights into Stress-Related Airway Vagal Excitation
The airway vagal preganglionic neurons (AVPNs) in the external formation of the nucleus ambiguus (eNA) play a major role in the… 
2012
2012
ifferential effects of osmotic and SSR 149415 challenges in maternally separated nd control rats : The role of vasopressin on spatial learning
Maternal separation (MS) has been demonstrated to up-regulate the hypothalamic vasopressin (VP) system. Intracerebrally released… 
2012
2012
The Vasopressin V 1 b Receptor Antagonist SSR 149415 in the Treatment of Major Depressive and Generalized Anxiety Disorders : Results From 4 Randomized , Double-Blind , Placebo-Controlled Studies
Objective: These studies were designed to evaluate the efficacy and tolerability of the first nonpeptide vasopressin V1b receptor… 
2011
2011
Congenital absence of vasopressin and age-dependent changes in ACTH and corticosterone stress responses in rats
The hypothalamic components of the hypothalamo–pituitary–adrenal axis (HPA) are corticotropin-releasing hormone (CRH) and… 
2011
2011
Effect of vasopressin V1b receptor antagonist, SSR149415, on anxiety-like behavior and Lewis lung carcinoma metastasis in mice.
AIM To study the effect of new vasopressin V1b receptor antagonist, SSR149415, on anxiety-like behavior and Lewis lung carcinoma… 
2008
2008
Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats
2006
2006
The vasopressin‐induced excitation of hypoglossal and facial motoneurons in young rats is mediated by V1a but not V1b receptors, and is independent of intracellular calcium signalling
As a hormone, vasopressin binds to three distinct receptors: V1a and V1b receptors, which induce phospholipase‐Cβ (PLC… 
2006
2006
Effects of the vasopressin (V1B) receptor antagonist, SSR149415, and the corticotropin-releasing factor 1 receptor antagonist, SSR125543, on FG 7142-induced increase in acetylcholine and…
Highly Cited
2005
Highly Cited
2005
Mechanisms of Cell-surface Rerouting of an Endoplasmic Reticulum-retained Mutant of the Vasopressin V1b/V3 Receptor by a Pharmacological Chaperone*
Cell-surface expression and biological functions of several intracellular-retained G protein-coupled receptors are restored by… 
2004
2004
Involvement of arginine vasopressin in endogenous central histamine-induced reversal of critical haemorrhagic hypotension in rats
AbstractObjective and design:Histamine is a potent stimulator of arginine vasopressin (AVP) release and therefore, the role of… 
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