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SSCP Analysis

Known as: Single-Strand Conformation Polymorphism Analysis, single-stranded conformation polymorphism analysis 
A procedure used to demonstrate nucleotide sequence variations that occur in the same region of DNA between individuals within a species, or between… 
National Institutes of Health

Papers overview

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Highly Cited
2003
Highly Cited
2003
Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features
Patients who have oligodendrogliomas (OD) that demonstrate loss of both 1p and 19q appear to have a better prognosis after they… 
Highly Cited
2002
Highly Cited
2002
Performance of cochlear implant recipients with GJB2-related deafness.
Congenital profound hearing loss affects 0.05-0.1% of children and has many causes, some of which are associated with cognitive… 
Highly Cited
2001
Highly Cited
2001
Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution
AbstractThe multidrug resistance protein 1 (MRP1) belonging to the ATP-binding cassette (ABC) superfamily of transport proteins… 
Highly Cited
1998
Highly Cited
1998
Risk of anal carcinoma in situ in relation to human papillomavirus type 16 variants.
Infection with human papillomavirus (HPV), especially HPV16, is central to the development of squamous anogenital cancers and… 
Highly Cited
1996
Highly Cited
1996
Molecular analysis of the FHIT gene at 3p14.2 in lung cancer cell lines.
Chromosome 3p is frequently deleted in various cancers including examples in the lung. A novel gene, termed FHIT, was recently… 
Highly Cited
1995
Highly Cited
1995
Molecular analysis of cutaneous B- and T-cell lymphomas.
Among extranodal non-Hodgkin's lymphomas, primary cutaneous lymphomas (CLs) represent a consistent group of B- and T-cell… 
Highly Cited
1994
Highly Cited
1994
Mutations of the p53 tumor suppressor gene occur infrequently in Wilms' tumor.
Mutations of the p53 tumor suppressor gene occur frequently in a variety of adult-onset tumors, including colon, breast, lung… 
Highly Cited
1994
Highly Cited
1994
Mutation rate of the CDKN2 gene in malignant gliomas.
The CDKN2 gene encodes p16, a protein controlling the cell cycle. CDKN2 is deleted in a relevant number of tumor cell lines, but… 
Highly Cited
1994
Highly Cited
1994
Further screening of the rhodopsin gene in patients with autosomal dominant retinitis pigmentosa.
Here the authors report 8 novel mutations and 8 previously reported mutations found from further analysis of the rhodopsin gene… 
Highly Cited
1993
Highly Cited
1993
Methods in laboratory investigation. Rapid and simple detection of c-Ki-ras2 gene codon 12 mutations by nonradioisotopic single-strand conformation polymorphism analysis.
BACKGROUND To achieve simple and rapid detection of codon 12 mutations of the c-Ki-ras2 gene, we developed a nonradioisotopic… 
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