SRPK1 gene

Known as: serine/arginine-rich splicing factor kinase 1, SR protein kinase 1, PROTEIN KINASE, ARGININE/SERINE-RICH SPLICING FACTOR, 1 
This gene is involved in both protein phosphorylation and RNA splicing.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2018
024619962018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
The therapeutic potential of cisplatin in ovarian cancer treatment is restricted by the occurrence of cellular resistance. We… (More)
Is this relevant?
2014
2014
Background:Current therapies for metastatic melanoma are targeted either at cancer mutations driving growth (e.g., vemurafenib… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2014
2014
Akt activation is a hallmark of human cancers. Here, we report a critical mechanism for regulation of Akt activity by the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2013
2013
Protein kinases are important regulators in biologic processes. Aberrant expression of protein kinases often causes diseases… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Angiogenesis is regulated by the balance of proangiogenic VEGF(165) and antiangiogenic VEGF(165)b splice isoforms. Mutations in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2007
2007
Human papillomavirus (HPV) infections of the squamous epithelium are associated with high-level expression of the E1circumflexE4… (More)
Is this relevant?
2005
2005
Assembly of the spliceosome requires the participation of SR proteins, a family of splicing factors rich in arginine-serine… (More)
Is this relevant?
2004
2004
Male germ cell tumors (GCTs) are extremely sensitive to platinum-containing chemotherapy, with only 10% of patients showing… (More)
Is this relevant?
2001
2001
The therapeutic potential of cisplatin, one of the most active and widely used anticancer drugs, is severely limited by the… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1996
Highly Cited
1996
Serine/arginine-rich (SR) proteins are essential for pre-mRNA splicing, and modify the choice of splice site during alternative… (More)
Is this relevant?