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SRPK1 gene

Known as: serine/arginine-rich splicing factor kinase 1, SR protein kinase 1, PROTEIN KINASE, ARGININE/SERINE-RICH SPLICING FACTOR, 1 
This gene is involved in both protein phosphorylation and RNA splicing.
National Institutes of Health

Related topics

Related topics

8 relations
Chromosome CondensationChromosome SegregationImmune responsePhosphorylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Serine-arginine protein kinase 1 (SRPK1) is elevated in gastric cancer and plays oncogenic functions
Serine-arginine protein kinase 1 (SRPK1) phosphorylates proteins involved in the regulation of several mRNA processing pathways… 
2017
2017
Enhancer of rudimentary homologue interacts with scaffold attachment factor B at the nuclear matrix to regulate SR protein phosphorylation
Scaffold attachment factor B1 (SAFB1) is an integral component of the nuclear matrix of vertebrate cells. It binds to DNA on… 
2014
2014
Serine–arginine protein kinase 1 is associated with breast cancer progression and poor patient survival
Abstract Breast cancer is the most common cancer and the second leading cause of mortality for women worldwide. It is necessary… 
2009
2009
Arginine Methylation of the ICP27 RGG Box Regulates the Functional Interactions of ICP27 with SRPK1 and Aly/REF during Herpes Simplex Virus 1 Infection
ABSTRACT The herpes simplex virus 1 protein ICP27 is methylated on arginine residues within an RGG box, and arginine methylation… 
2008
2008
SRPK1: A cisplatin sensitive protein expressed in retinoblastoma
Chemotherapy is an essential modality in the treatment of retinoblastoma (RB). Mammalian serine/arginine‐rich protein‐specific… 
2007
2007
The E1circumflexE4 protein of human papillomavirus interacts with the serine-arginine-specific protein kinase SRPK1.
Human papillomavirus (HPV) infections of the squamous epithelium are associated with high-level expression of the E1circumflexE4… 
Highly Cited
2004
Highly Cited
2004
Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.
Male germ cell tumors (GCTs) are extremely sensitive to platinum-containing chemotherapy, with only 10% of patients showing… 
Highly Cited
2001
Highly Cited
2001
Cloning and Characterization of an Alternatively Spliced Form of SR Protein Kinase 1 That Interacts Specifically with Scaffold Attachment Factor-B*
Serine/arginine protein kinases have been conserved throughout evolution and are thought to play important roles in the… 
1999
1999
SRPK1 and LBR protein kinases show identical substrate specificities.
Arginine/serine protein kinases constitute a novel class of enzymes that can modify arginine/serine (RS) dipeptide motifs. SR… 
1999
1999
Localization of serine kinases, SRPK1 (SFRSK1) and SRPK2 (SFRSK2), specific for the SR family of splicing factors in mouse and human chromosomes.
The serine- and arginine-rich (SR) splicing factors play an important role in both constitutive and alternative pre-mRNA splicing… 
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