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SR 27417

Known as: SR-27417, SR27417A 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Structural basis for signal recognition and transduction by platelet-activating-factor receptor
Platelet-activating-factor receptor (PAFR) responds to platelet-activating factor (PAF), a phospholipid mediator of cell-to-cell… 
2001
2001
Papel patogenetico del factor de activacion plaquetaria y el oxido nitrico endogeno en el asma bronquial
Distintas evidencias sugieren que el factor de activacion plaquetaria (PAF)y el oxido nitrico (NO) estarian involucradas en la… 
1998
1998
Lack of effectiveness of the platelet-activating factor antagonist SR27417A in patients with active ulcerative colitis: a randomized controlled trial. The Platelet Activating Factor Antagonist Study…
1998
1998
[Effect of calcium overload and platelet activating factor on calcitonin gene related peptide release from lung tissue].
The level of calcitonin gene related peptide (CGRP) in plasma and pulmonary lavage fluid was tested by radio-immunoassay on… 
Highly Cited
1997
Highly Cited
1997
Effects of a potent platelet-activating factor antagonist, SR27417A, on allergen-induced asthmatic responses.
Platelet-activating factor (PAF) is a lipid-derived mediator that has been implicated in the pathophysiology of airway… 
1995
1995
Platelet-activating factor stimulates gastric acid secretion in isolated rabbit gastric glands.
We examined the effect of platelet-activating factor (PAF) on gastric acid secretion by isolated rabbit gastric glands as… 
1994
1994
Effect of platelet activating factor antagonists in different models of thrombosis.
1992
1992
Effect of SR 27417 on oedema formation induced in rabbit skin by platelet-activating factor or antigen.
1991
1991
Biochemical and pharmacological activities of SR 27417, a highly potent, long-acting platelet-activating factor receptor antagonist.
SR 27417 [N-(2-dimethylamino ethyl)-N-(3-pyridinyl methyl)[4- (2,4,6-triisopropylphenyl) thiazol-2-yl]amine] is the first member… 
1991
1991
Protective effect of SR 27417, a novel PAF antagonist, on lethal anaphylactic and endotoxin-induced shock in mice.
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