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SPT5 transcriptional elongation factor

Known as: SPT5 Protein, hSPT5, DSIF Large Subunit 
Transcription elongation factor SPT5 (1087 aa, ~121 kDa) is encoded by the human SUPT5H gene. This protein plays a role in both transcriptional… Expand
National Institutes of Health

Papers overview

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2018
2018
Microsatellite expansions cause more than 40 neurological disorders, including Huntington's disease, myotonic dystrophy, and… Expand
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2018
2018
The intracellular pathogen Legionella pneumophila influences numerous eukaryotic cellular processes through the Dot/Icm‐dependent… Expand
2015
2015
The human telomerase reverse transcriptase (hTERT) promoter promotes differential hTERT gene expression in tumor cells and normal… Expand
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Highly Cited
2001
Highly Cited
2001
  • Jae B. Kim, P. Sharp
  • The Journal of Biological Chemistry
  • 2001
  • Corpus ID: 41435057
The CDK9-cyclin T kinase complex, positive transcription elongation factor b (P-TEFb), stimulates the process of elongation of… Expand
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Highly Cited
2001
Highly Cited
2001
We identify and characterize several phosphorylated forms of the hSpt5 subunit of the DRB sensitivity-inducing factor (DSIF). A… Expand
Highly Cited
1999
Highly Cited
1999
RNA polymerase II nascent transcripts are capped during pausing before elongation. Here we report that hSPT5, the human homolog… Expand
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Highly Cited
1999
Highly Cited
1999
ABSTRACT The potent transactivator Tat recognizes the transactivation response RNA element (TAR) of human immunodeficiency virus… Expand
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1999
1999
The potent transactivator Tat recognizes the transactivation response RNA element (TAR) of human immunodeficiency virus type 1… Expand
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Highly Cited
1998
Highly Cited
1998
We report the identification of a transcription elongation factor from HeLa cell nuclear extracts that causes pausing of RNA… Expand
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1996
1996
We isolated the human homologue, SUPT5H, of the yeast transcription factor, SPT5. The human homologue is 1088 aa long compared to… Expand