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SPT5 transcriptional elongation factor

Known as: SPT5 Protein, hSPT5, DSIF Large Subunit 
Transcription elongation factor SPT5 (1087 aa, ~121 kDa) is encoded by the human SUPT5H gene. This protein plays a role in both transcriptional… Expand
National Institutes of Health

Papers overview

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2018
2018
Microsatellite expansions cause more than 40 neurological disorders, including Huntington's disease, myotonic dystrophy, and… Expand
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2018
2015
2015
The human telomerase reverse transcriptase (hTERT) promoter promotes differential hTERT gene expression in tumor cells and normal… Expand
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Highly Cited
2001
Highly Cited
2001
The CDK9-cyclin T kinase complex, positive transcription elongation factor b (P-TEFb), stimulates the process of elongation of… Expand
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2001
2001
We identify and characterize several phosphorylated forms of the hSpt5 subunit of the DRB sensitivity-inducing factor (DSIF). A… Expand
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Highly Cited
1999
Highly Cited
1999
RNA polymerase II nascent transcripts are capped during pausing before elongation. Here we report that hSPT5, the human homolog… Expand
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1999
1999
The potent transactivator Tat recognizes the transactivation response RNA element (TAR) of human immunodeficiency virus type 1… Expand
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1999
1999
The potent transactivator Tat recognizes the transactivation response RNA element (TAR) of human immunodeficiency virus type 1… Expand
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Highly Cited
1998
Highly Cited
1998
We report the identification of a transcription elongation factor from HeLa cell nuclear extracts that causes pausing of RNA… Expand
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1996
1996
We isolated the human homologue, SUPT5H, of the yeast transcription factor, SPT5. The human homologue is 1088 aa long compared to… Expand
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