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SPT5 transcriptional elongation factor
Known as:
SPT5 Protein
, hSPT5
, DSIF Large Subunit
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Transcription elongation factor SPT5 (1087 aa, ~121 kDa) is encoded by the human SUPT5H gene. This protein plays a role in both transcriptional…
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National Institutes of Health
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Related topics
Related topics
13 relations
Chromatin Remodeling Factor
Genes, Regulator
Nucleoplasm
Protein Complex Subunit
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Broader (2)
Chromosomal Proteins, Non-Histone
Transcriptional Elongation Factors
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
Repeat-associated non-ATG (RAN) translation
J. Cleary
,
Amrutha Pattamatta
,
L. Ranum
The Journal of Biological Chemistry
2018
Corpus ID: 52273829
Microsatellite expansions cause more than 40 neurological disorders, including Huntington's disease, myotonic dystrophy, and…
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2018
2018
Targeting of RNA Polymerase II by a nuclear Legionella pneumophila Dot/Icm effector SnpL
R. Schuelein
,
H. Spencer
,
+12 authors
E. Hartland
Cellular microbiology
2018
Corpus ID: 13800343
The intracellular pathogen Legionella pneumophila influences numerous eukaryotic cellular processes through the Dot/Icm‐dependent…
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2015
2015
Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells
Rui Chen
,
Jing Zhu
,
Yong Dong
,
Chao He
,
Xiaotong Hu
Oncotarget
2015
Corpus ID: 38415462
The human telomerase reverse transcriptase (hTERT) promoter promotes differential hTERT gene expression in tumor cells and normal…
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Highly Cited
2001
Highly Cited
2001
Positive Transcription Elongation Factor b Phosphorylates hSPT5 and RNA Polymerase II Carboxyl-terminal Domain Independently of Cyclin-dependent Kinase-activating Kinase*
Jae B. Kim
,
P. Sharp
The Journal of Biological Chemistry
2001
Corpus ID: 41435057
The CDK9-cyclin T kinase complex, positive transcription elongation factor b (P-TEFb), stimulates the process of elongation of…
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Highly Cited
2001
Highly Cited
2001
The peptidyl-prolyl isomerase Pin1 interacts with hSpt5 phosphorylated by Cdk9.
S. Lavoie
,
A. Albert
,
H. Handa
,
M. Vincent
,
O. Bensaude
Journal of molecular biology
2001
Corpus ID: 31278040
We identify and characterize several phosphorylated forms of the hSpt5 subunit of the DRB sensitivity-inducing factor (DSIF). A…
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Highly Cited
1999
Highly Cited
1999
Transcription elongation factor hSPT5 stimulates mRNA capping.
Y. Wen
,
A. Shatkin
Genes & development
1999
Corpus ID: 6672184
RNA polymerase II nascent transcripts are capped during pausing before elongation. Here we report that hSPT5, the human homolog…
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Highly Cited
1999
Highly Cited
1999
Tat-SF1 Protein Associates with RAP30 and Human SPT5 Proteins
Jae B. Kim
,
Y. Yamaguchi
,
T. Wada
,
H. Handa
,
P. Sharp
Molecular and Cellular Biology
1999
Corpus ID: 13151516
ABSTRACT The potent transactivator Tat recognizes the transactivation response RNA element (TAR) of human immunodeficiency virus…
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1999
1999
Tat-SF 1 Protein Associates with RAP 30 and Human SPT 5 Proteins
Jae B. Kim
,
Y. Yamaguchi
,
T. Wada
,
H. Handa
,
P. Sharp
1999
Corpus ID: 6758989
The potent transactivator Tat recognizes the transactivation response RNA element (TAR) of human immunodeficiency virus type 1…
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Highly Cited
1998
Highly Cited
1998
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs.
T. Wada
,
T. Takagi
,
+9 authors
H. Handa
Genes & development
1998
Corpus ID: 30303097
We report the identification of a transcription elongation factor from HeLa cell nuclear extracts that causes pausing of RNA…
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1996
1996
Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5.
P. Chiang
,
E. Fogel
,
+5 authors
D. Kurnit
Genomics
1996
Corpus ID: 38238919
We isolated the human homologue, SUPT5H, of the yeast transcription factor, SPT5. The human homologue is 1088 aa long compared to…
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