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SPRY1 gene

Known as: hSPRY1, SPRY1, Sprouty Homolog 1, Antagonist of FGF Signaling (Drosophila) Gene 
This gene may play a role in both signaling and organogenesis.
National Institutes of Health

Related topics

Related topics

1 relation
Signal Transduction

Papers overview

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2020
2020
Mechanism of SPRY1 methylation regulating natural aging of skin epidermal cells
To investigate the relationship among natural aging of epidermal cells, epigenetics, and SPRY1 methylation mechanism. 
2019
2019
MicroRNA-421 promotes inflammatory response of fibroblast-like synoviocytes in rheumatoid arthritis by targeting SPRY1.
OBJECTIVE The aim of this study was to investigate whether microRNA-421 could participate in the proliferative, migratory and… 
2019
2019
[Tolvaptan attenuates atrial remodeling in rats undergoing chronic intermittent hypoxia via miRNA-21].
Objective: To investigate the effects and potential mechanisms of tolvaptan on chronic intermittent hypoxia (CIH)-induced atrial… 
2019
2019
Sprouty1 regulates neuritogenesis and survival of cortical neurons
In multicellular organisms, receptor tyrosine kinases (RTKs) control a variety of cellular processes, including cell… 
2018
2018
Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen‐mediated changes in cell cycle regulatory circuits
Signals from growth factors or mechanical stimuli converge to promote vascular smooth muscle cell (VSMC) migration and… 
2017
2017
IGFBP2 induces SPRY1 expression via NF-κB signaling pathway in glioblastoma multiforme (GBM).
OBJECTIVE Gliomas are accompanied with high mortality owning to their invasive peculiarity and vulnerability to drug resistance… 
2014
2014
SPRY1 promotes the degradation of uPAR and inhibits uPAR-mediated cell adhesion and proliferation.
Urokinase plasminogen activator receptor (uPAR) is a GPI anchored cell surface protein that is closely associated with invasion… 
2013
2013
Human Sprouty1 Suppresses Urokinase Receptor-Stimulated Cell Migration and Invasion
The urokinase-type plasminogen activator receptor (uPAR) has been implicated in several processes in tumor progression including… 
2011
2011
Spry1 Is Expressed in Hemangioblasts and Negatively Regulates Primitive Hematopoiesis and Endothelial Cell Function
Background Development of the hematopoietic and endothelial lineages derives from a common mesodermal precursor, the Flk1… 
2011
2011
Transcriptional and post-transcriptional regulation of Sprouty1, a receptor tyrosine kinase inhibitor in prostate cancer
Sprouty1 (Spry1) is a negative regulator of fibroblast growth factor signaling with a potential tumor suppressor function in… 
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