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SPRTN gene

Known as: DVC1, DKFZP547N043, DNA damage-targeting VCP (p97) adaptor 
 
National Institutes of Health

Papers overview

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Highly Cited
2018
Highly Cited
2018
Background Apalutamide, a competitive inhibitor of the androgen receptor, is under development for the treatment of prostate… Expand
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Review
2017
Review
2017
Covalent DNA–protein crosslinks (DPCs, also known as protein adducts) of topoisomerases and other proteins with DNA are highly… Expand
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Highly Cited
2016
Highly Cited
2016
Summary Covalent DNA-protein crosslinks (DPCs) are toxic DNA lesions that interfere with essential chromatin transactions, such… Expand
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Highly Cited
2014
Highly Cited
2014
Spartan (also known as DVC1 and C1orf124) is a PCNA-interacting protein implicated in translesion synthesis, a DNA damage… Expand
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Highly Cited
2012
Highly Cited
2012
Ubiquitin-mediated processes orchestrate critical DNA-damage signaling and repair pathways. We identify human DVC1 (C1orf124… Expand
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Highly Cited
2012
Highly Cited
2012
Ubiquitin-binding domains (UBDs) are crucial for recruiting many proteins to sites of DNA damage. Here we characterize C1orf124… Expand
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Highly Cited
2012
Highly Cited
2012
Background: Translesion synthesis involves proliferating cell nuclear antigen (PCNA) monoubiquitination and polymerase switching… Expand
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Highly Cited
2012
Highly Cited
2012
Uninterrupted replication across damaged DNA is critical to prevent replication fork collapse and resulting double-strand DNA… Expand
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Highly Cited
2011
Highly Cited
2011
This paper presents the design and development of dynamic partially reconfigurable pulsewidth modulation (DPRPWM) controller for… Expand
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2007
2007
Traffic light controller establishes a set of rules and instructions that drivers, pilots, train engineers, and ship captains… Expand
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