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SPRED2 gene
Known as:
SPRED2
, Spred-2
, FLJ31917
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
SPRED2 deficiency may lead to lung ischemia–reperfusion injury via ERK1/2 signaling pathway activation
M. Okada
,
M. Yamane
,
+7 authors
S. Miyoshi
Surgery Today
2018
Corpus ID: 49869013
PurposeInflammatory changes during lung ischemia–reperfusion injury (IRI) are related to the activation of the extracellular…
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2016
2016
A Novel Role of Spred2 in the Colonic Epithelial Cell Homeostasis and Inflammation
Sakuma Takahashi
,
T. Yoshimura
,
+8 authors
A. Matsukawa
Scientific reports
2016
Corpus ID: 9931331
Rapid and adequate mucosal healing is important for a remission of ulcerative colitis (UC) patients. Here, we examined whether…
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2016
2016
Tumor suppressor Spred2 interaction with LC3 promotes autophagosome maturation and induces autophagy-dependent cell death
K. Jiang
,
Min Liu
,
+11 authors
Songshu Meng
Oncotarget
2016
Corpus ID: 17111680
The tumor suppressor Spred2 (Sprouty-related EVH1 domain-2) induces cell death in a variety of cancers. However, the underlying…
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2015
2015
Negative regulation of TGFβ-induced lens epithelial to mesenchymal transition (EMT) by RTK antagonists.
Guannan Zhao
,
Magdalena C. Wojciechowski
,
S. Jee
,
J. Boros
,
J. McAvoy
,
F. Lovicu
Experimental eye research
2015
Corpus ID: 30732650
2013
2013
Evidence for downregulation of the negative regulator SPRED2 in clinical prostate cancer
N. Kachroo
,
T. Valencia
,
A. Warren
,
V. Gnanapragasam
British Journal of Cancer
2013
Corpus ID: 15530549
Background:SPRED1 and 2 are key negative regulators of MAPK signalling in mammalian cells. Here, we investigate the expression…
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2012
2012
Tyrosines 303/343/353 within the Sprouty-related domain of Spred2 are essential for its interaction with p85 and inhibitory effect on Ras/ERK activation.
Songshu Meng
,
Miao Zhang
,
+5 authors
Chuangui Wang
The international journal of biochemistry & cell…
2012
Corpus ID: 45272319
2011
2011
Regulation of human hepatocellular carcinoma cells by Spred2 and correlative studies on its mechanism.
Xiao-ni Ma
,
Xiao-Yun Liu
,
+7 authors
Hua Wang
Biochemical and biophysical research…
2011
Corpus ID: 36131384
2010
2010
Spred2 is involved in imatinib-induced cytotoxicity in chronic myeloid leukemia cells.
Xiao-Yun Liu
,
Yuefeng Yang
,
+7 authors
Li-Sheng Wang
Biochemical and biophysical research…
2010
Corpus ID: 20005877
2010
2010
Spred2 expression during mouse development
I. Tuduce
,
K. Schuh
,
K. Bundschu
Developmental dynamics : an official publication…
2010
Corpus ID: 29907173
SPREDs (Sprouty‐related proteins with Ena/Vasodilator‐stimulated phosphoprotein homology‐1 domain) are known membrane‐associated…
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2010
2010
Spred2 inhibits TGF‐β1‐induced urokinase type plasminogen activator expression, cell motility and epithelial mesenchymal transition
Victor Villar
,
J. Kocić
,
J. Santibañez
International journal of cancer
2010
Corpus ID: 24486124
TGF‐β1 is a potent inductor of malignance in cancer cells. TGF‐β1 stimulates the expression of extracellular matrix degrading…
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