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SPP1 wt Allele

Known as: Early T-Lymphocyte Activation 1 Gene, PSEC0156, BNSP 
Human SPP1 wild-type allele is located in the vicinity of 4q22.1 and is approximately 8 kb in length. This allele, which encodes osteopontin protein… Expand
National Institutes of Health

Papers overview

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Review
2010
Review
2010
Macrophages are found in close proximity with collagen-producing myofibroblasts and indisputably play a key role in fibrosis… Expand
Highly Cited
2003
Highly Cited
2003
We have recently reported that osteopontin (OPN) stimulates tumor growth and activation of promatrix metalloproteinase-2 (pro-MMP… Expand
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Highly Cited
2000
Highly Cited
2000
Cell-mediated (type-1) immunity is necessary for immune protection against most intracellular pathogens and, when excessive, can… Expand
Review
2000
Review
2000
Osteopontin (Opn) is a secreted adhesive, glycosylated phosphoprotein that contains the arginine‐glycine‐aspartic acid (RGD) cell… Expand
Highly Cited
2000
Highly Cited
2000
Oncogenic hypophosphatemic osteomalacia (OHO) is characterized by a renal phosphate leak, hypophosphatemia, low-serum calcitriol… Expand
Review
2000
Review
2000
Abstract Previously regarded as an adhesive bone matrix protein, recent studies suggest that osteopontin (Eta-1) is also a novel… Expand
Highly Cited
1996
Highly Cited
1996
The CD44 family of surface receptors regulates adhesion, movement, and activation of normal and neoplastic cells. The cytokine… Expand
Highly Cited
1990
Highly Cited
1990
A human osteopontin (OP) cDNA was isolated from a library made from primary cultures of human bone cells. The distribution of… Expand
Highly Cited
1990
Highly Cited
1990
The Eta-1 gene specifies a secreted product of activated T cells and is associated with genetic resistance to infection by an… Expand
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Highly Cited
1989
Highly Cited
1989
We describe a murine cDNA, designated Early T lymphocyte activation 1 (ETA-1) which is abundantly expressed after activation of T… Expand
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