SPOP gene

Known as: SPECKLE-TYPE POZ PROTEIN, SPOP, Speckle-Type POZ Protein Gene 
This gene may be involved in both transcriptional repression and protein ubiquitination.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
  • The Cancer, Genome Atlas Research Network
  • Cell
  • 2015
There is substantial heterogeneity among primary prostate cancers, evident in the spectrum of molecular abnormalities and its… (More)
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Highly Cited
2013
Highly Cited
2013
The p160 steroid receptor coactivators (SRCs) SRC-1, SRC-2 [nuclear receptor coactivator (NCOA)2], and SRC-3 [amplified in breast… (More)
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Highly Cited
2012
Highly Cited
2012
Prostate cancer is the second most common cancer in men worldwide and causes over 250,000 deaths each year. Overtreatment of… (More)
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Highly Cited
2012
Highly Cited
2012
Endometrial cancer is the sixth most commonly diagnosed cancer in women worldwide, causing ∼74,000 deaths annually. Serous… (More)
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Highly Cited
2011
Highly Cited
2011
Steroid receptor co-activator-3 (SRC-3/AIB1) is an oncogene that is amplified and overexpressed in many human cancers. However… (More)
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Highly Cited
2010
Highly Cited
2010
Gli2 and Gli3 are primary transcriptional regulators that mediate hedgehog (Hh) signaling. Mechanisms that stabilize and… (More)
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Highly Cited
2009
Highly Cited
2009
In the largest E3 ligase subfamily, Cul3 binds a BTB domain, and an associated protein-interaction domain such as MATH recruits… (More)
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Highly Cited
2008
Highly Cited
2008
RT-qPCR is a preferred method for rapid and reliable quantification of gene expression studies. Appropriate application of RT… (More)
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Highly Cited
2005
Highly Cited
2005
X inactivation involves the stable silencing of one of the two X chromosomes in XX female mammals. Initiation of this process… (More)
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Highly Cited
1999
Highly Cited
1999
The HM loci in Saccharomyces cerevisiae constitute region-specific but gene-nonspecific repression domains, as a number of… (More)
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