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SPIO Nanoparticle

Known as: Amino Dextran-Coated Iron Oxide Particle, SPIO 
Nanoparticles that have been functionalized with chemical amine groups and dextran. These particles have been utilized as magnetic resonance imaging… 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
A molecular MRI probe to detect treatment of cardiac apoptosis in vivo
Cell death by apoptosis is critical in myocardial diseases, and noninvasive detection of early, reversible apoptosis might be… 
Highly Cited
2009
Highly Cited
2009
Inhibited atherosclerotic plaque formation by local administration of magnetically labeled endothelial progenitor cells (EPCs) in a rabbit model.
Highly Cited
2009
Highly Cited
2009
Self-assembly of magnetite nanocrystals with amphiphilic polyethylenimine: structures and applications in magnetic resonance imaging.
Controlled self-assembly of magnetic nanocrystals has important applications in biomedical fields. In this study, hydrophobic… 
Highly Cited
2008
Highly Cited
2008
Nanoimmunoliposome delivery of superparamagnetic iron oxide markedly enhances targeting and uptake in human cancer cells in vitro and in vivo.
Highly Cited
2008
Highly Cited
2008
Asialoglycoprotein receptor-targeted superparamagnetic iron oxide nanoparticles.
2008
2008
In vivo serial evaluation of superparamagnetic iron‐oxide labeled stem cells by off‐resonance positive contrast
MRI is emerging as a diagnostic modality to track iron‐oxide‐labeled stem cells. This study investigates whether an off‐resonance… 
Highly Cited
2003
Highly Cited
2003
Superparamagnetic iron oxide particles transactivator protein-fluorescein isothiocyanate particle labeling for in vivo magnetic resonance imaging detection of cell migration: uptake and durability
Conjugation of dextran-coated superparamagnetic iron oxide (SPIO) particles with transactivator protein (Tat)-peptide and… 
Highly Cited
2002
Highly Cited
2002
How to detect hepatocellular carcinoma in cirrhosis
Abstract. Cirrhosis predisposes to hepatocellular carcinoma (HCC) which develops by sequential steps of de-differentiation of… 
Highly Cited
1999
Highly Cited
1999
MRI‐guided radiofrequency thermal ablation of implanted VX2 liver tumors in a rabbit model: Demonstration of feasibility at 0.2 T
Successful radiofrequency (RF) thermal ablation was performed on VX2 tumors implanted in 23 rabbit livers under magnetic… 
1994
1994
Effects of spatial distribution on proton relaxation enhancement by particulate iron oxide
The proton relaxation effect of superparamagnetic iron oxide (SPIO) particles under varying conditions of spatial distribution… 
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