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SPC 703

Known as: SPC-703 
National Institutes of Health

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1 relation

Broader (1)

glipalamide

Papers overview

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1988
1988
Sulphonylureas-Induced Increase in Insulin Binding and Glucose Metabolism by Isolated Rat Adipocytes
The effects of oral hypoglycaemic drugs, SPC-703 (n-/p-toluenesulphonyl/-5-methyl-2-pirazoline-1-carbonami de) and tolbutamide on… 
1985
1985
[Clinical evaluation of a new sulfonylurea derivative, preparation SPC-703, based on a 5-year observation].
1984
1984
Effect of sulphonylurea derivatives, SPC-703 and tolbutamide, on insulin binding by isolated rat adipocytes.
The effect of oral hypoglycaemic drugs, SPC-703 [n-(p-toluenesulphonyl)-5-methyl-2-pirazoline-1-carbonami de] and tolbutamide on… 
1981
1981
[Effect of long-term therapy with a new sulfonylurea derivative SPC-703 on the endocrine function of the pancreas in adult-onset diabetic patients].
1980
1980
Pharmacokinetics of a new hypoglycemic agent SPC-703.
Pharmacokinetic of a new hypoglycemic agent, SPC-703 was studied in rats after iv, ip and po administration of two doses of the… 
1980
1980
Biotransformation of a new hypoglycemic agent, N-(p-toluenesulfonyl)-5-methyl-2-pyrazoline-1-carbonamide (SPC-703) in humans and rats.
Over 60% of a dose of N-(p-toluenesulfonyl)-5-methyl-2-pyrazoline-1-carbonamide (SPC-703) given to humans or rats was excreted… 
1979
1979
The influence of SPC-703 on blood pressure in rabbits and rats and on isolated heart of guinea pigs.
New oral hypoglycemic drug, SPC-703, given in doses of 100 and 200 mg/kg iv rised the arterial pressure in the rat. In the… 
1977
1977
Binding of sulfonylurea derivatives to bovine serum albumin: part II. The relationship of binding to albumin, chemical structure, and hypoglycemic activity of sulfonamide derivatives of 2-pyrazoline…
The relationship of binding to protein and hypoglycemic activity of 11 sulfonamide derivatives of 2-pyrazoline-1-carboxamide was… 
1976
1976
Influence of some salicylates and sulfonamides on binding by albumin of SPC-703 and tolbutamide.
Bovine serum albumin has two different binding sites for sulfonylurea. The sites at high affinity can bind up to 2 moles of a new… 
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