Skip to search formSkip to main contentSkip to account menu

SPARCL1 protein, human

Known as: High Endothelial Venule Protein, Proliferation-Inducing Protein 33, SPARC-like 1 (mast9, hevin) protein, human 
SPARC-like protein 1 (664 aa, ~75 kDa) is encoded by the human SPARCL1 gene. This protein may be involved in both leukocyte extravasation and… 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (2)

Calcium-Binding ProteinsExtracellular Matrix Proteins
Extracellular SpaceGenes, RegulatorSPARCL1 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Modulation of SPARC/Hevin Proteins in Alzheimer’s Disease Brain Injury
Alzheimer’s disease (AD) is an age-related progressive form of dementia that features neuronal loss, intracellular tau, and… 
2019
2019
Cartography of hevin-expressing cells in the adult brain reveals prominent expression in astrocytes and parvalbumin neurons
Hevin, also known as SPARC-like 1, is a member of the secreted protein acidic and rich in cysteine family of matricellular… 
2011
2011
Effect of hevin deletion in mice and characterization in trabecular meshwork.
PURPOSE Hevin is a matricellular protein and the result of a gene duplication of SPARC. SPARC-null mice have lower intraocular… 
2008
2008
Altered tissue repair in hevin‐null mice: Inhibition of fibroblast migration by a matricellular SPARC homolog
Matricellular proteins such as hevin, secreted protein acidic and rich in cysteine, and thrombospondin‐2 play an important role… 
Highly Cited
2006
Highly Cited
2006
Matricellular Hevin Regulates Decorin Production and Collagen Assembly*
Matricellular proteins such as SPARC, thrombospondin 1 and 2, and tenascin C and X subserve important functions in extracellular… 
Highly Cited
2006
Highly Cited
2006
SPARC and Hevin expression correlate with tumour angiogenesis in hepatocellular carcinoma
Both Secreted Protein Acidic and Rich in Cysteine (SPARC) and Hevin are multifunctional matricellular glycoproteins. Recent… 
2006
2006
The amelogenin story: origin and evolution.
Genome sequencing and gene mapping have permitted the identification of HEVIN (SPARC-Like1) as the probable ancestor of the… 
Review
2004
Review
2004
Hevin/SC1, a matricellular glycoprotein and potential tumor-suppressor of the SPARC/BM-40/Osteonectin family.
Highly Cited
2000
Highly Cited
2000
Hevin is down-regulated in many cancers and is a negative regulator of cell growth and proliferation
We have cloned a human Hevin cDNA from omental adipose tissue of different patients by reverse transcription polymerase chain… 
Highly Cited
1998
Highly Cited
1998
Characterization of MAST9/Hevin, a SPARC-like protein, that is down-regulated in non-small cell lung cancer.
In the search for genes down-regulated in non-small cell lung cancer (NSCLC), we have identified a cDNA fragment, termed MAST9… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)