SPARC gene

Known as: Secreted Protein, Acidic, Cysteine-Rich (Osteonectin) Gene, SECRETED PROTEIN, ACIDIC, CYSTEINE-RICH, secreted protein acidic and cysteine rich 
This gene is involved in the regulation of cellular morphology, extracellular matrix deposition and cell cycle progression.

Topic mentions per year

Topic mentions per year

1986-2018
0102019862018

Papers overview

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2011
2011
BACKGROUND The extracellular matrix protein SPARC (Secreted Protein, Acidic, Rich in Cysteine) has been linked to degeneration of… (More)
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Highly Cited
2011
Highly Cited
2011
PURPOSE The trial objectives were to identify the maximum-tolerated dose (MTD) of first-line gemcitabine plus nab-paclitaxel in… (More)
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2010
2010
Advanced age, independent of concurrent cardiovascular disease, can be associated with increased extracellular matrix (ECM… (More)
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Highly Cited
2007
Highly Cited
2007
Secreted protein acidic and rich in cysteine (SPARC) is an extracellular glycoprotein expressed in several solid cancers… (More)
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2007
2006
2006
Age-related macular degeneration (AMD) is characterized by progressive loss of central vision, which is attributed to abnormal… (More)
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2001
2001
PURPOSE We analyzed the gene expression of the glycoprotein termed secreted protein, acidic and rich in cysteine (SPARC), also… (More)
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Highly Cited
1998
Highly Cited
1998
SPARC (secreted protein acidic and rich in cysteine, also known as osteonectin/BM40) is a secreted Ca2+-binding glycoprotein that… (More)
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1994
1994
LIM domains are present in a number of proteins including transcription factors, a proto-oncogene product, and the adhesion… (More)
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Highly Cited
1993
Highly Cited
1993
SPARC (osteonectin/BM40) is a secreted protein that modifies the interaction of cells with extracellular matrix (ECM). When we… (More)
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