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SOX12 gene

Known as: SRY-BOX 22, SRY-box 12, SOX22 
National Institutes of Health

Papers overview

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2020
2020
Sox12 enhances Fbw7-mediated ubiquitination and degradation of GATA3 in Th2 cells
Allergic asthma that is caused by inhalation of house dust mites (HDMs) is mainly mediated by Th2 cells. Recently, the roles of… 
2018
2018
Sox12 promotes T reg differentiation in the periphery during colitis
Peripherally induced regulatory T (pT reg) cells play indispensable roles in regulating gut inflammation; however, the mechanism… 
2017
2017
Sox12 Is a Cancer Stem-Like Cell Marker in Hepatocellular Carcinoma
Recent studies on molecular carcinogenesis suggest that the chemo-resistance of some cancers is largely due to presence of cancer… 
2016
2016
Silencing of SOX12 by shRNA suppresses migration, invasion and proliferation of breast cancer cells
SOX12 mRNA expression was up-regulated in human breast cancer tissues. SOX12 was critical for cell migration, invasion and… 
Highly Cited
2015
Highly Cited
2015
Sox12, a direct target of FoxQ1, promotes hepatocellular carcinoma metastasis through up‐regulating Twist1 and FGFBP1
Metastasis is the main reason for high recurrence and poor survival of hepatocellular carcinoma (HCC) after curative resection… 
Highly Cited
2010
Highly Cited
2010
Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors
During organogenesis, neural and mesenchymal progenitor cells give rise to many cell lineages, but their molecular requirements… 
2009
2009
Genetic alterations and chemosensitivity profile in newly established human renal collecting duct carcinoma cell lines
To determine the genetic alterations and chemosensitivity profile of collecting duct carcinoma (CDC) of the kidney, as it is a… 
Highly Cited
2008
Highly Cited
2008
The three SoxC proteins—Sox4, Sox11 and Sox12—exhibit overlapping expression patterns and molecular properties
The group C of Sry-related high-mobility group (HMG) box (Sox) transcription factors has three members in most vertebrates: Sox4… 
Highly Cited
2008
Highly Cited
2008
Sox12 Deletion in the Mouse Reveals Nonreciprocal Redundancy with the Related Sox4 and Sox11 Transcription Factors
ABSTRACT The transcription factors Sox4 and Sox11 are important regulators of diverse developmental processes including heart… 
Highly Cited
1997
Highly Cited
1997
SOX22 is a new member of the SOX gene family, mainly expressed in human nervous tissue.
SOX (SRY box-containing) genes share a particular DNA-binding domain, called HMG, with the mammalian testis-determining gene SRY… 
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