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The mitochondrial virus-induced signaling adaptor (VISA, also called mitochondrial antiviral signaling, MAVS) protein is a… Expand MITA (also called STING) is a central adaptor protein in innate immune response to cytosolic DNA. Cellular trafficking of MITA… Expand Significance IFNγ is a cytokine that induces various downstream genes for host defense against pathogens. How IFNγ induces… Expand SNX8: A Candidate Gene for 7p22 Cardiac Malformations Including Tetralogy of Fallot Rena J. Vanzo,* Megan M. Martin, Mallory R… Expand
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Endosomal sorting is essential for cell homeostasis. Proteins targeted for degradation are retained in the maturing endosome… Expand Late-onset Alzheimer's disease (LOAD) is a complex and multifactorial disease. So far ten loci have been identified for LOAD… Expand Sorting nexin 8 (SNX8) belongs to the sorting nexin protein family, whose members are involved in endocytosis and endosomal… Expand A hex-1 homolog named MVP1 was isolated from an appressoria cDNA library of the rice blast fungus Magnaporthe grisea. The… Expand The VPS1 gene of Saccharomyces cerevisiae encodes an 80-kDa GTPase that associates with Golgi membranes and is required for the… Expand