Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

SNX6 gene

Known as: SNX6, SORTING NEXIN 6 
 
National Institutes of Health

Related topics

Related topics

1 relation
SNX16 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Cargo-selective SNX-BAR proteins mediate retromer trimer independent retrograde transport
The retromer complex, which recycles the cation-independent mannose 6-phosphate receptor (CI-MPR) from endosomes to the trans… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 6
Is this relevant?
2016
2016
miR-98-5p Acts as a Target for Alzheimer’s Disease by Regulating Aβ Production Through Modulating SNX6 Expression
Accumulation of amyloid β-peptide (Aβ) in the brain of Alzheimer disease (AD) patients is believed to be the main pathological… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2013
2013
PtdIns(4)P regulates retromer–motor interaction to facilitate dynein–cargo dissociation at the trans-Golgi network
The molecular mechanisms for the retrograde motor dynein–dynactin to unload its cargoes at their final destination remain to be… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2010
2010
Tumor suppressor p27(Kip1) undergoes endolysosomal degradation through its interaction with sorting nexin 6.
A large body of evidence supports the hypothesis that proteasomal degradation of the growth suppressor p27(Kip1) (p27… Expand
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing.
The beta-site APP cleaving enzyme-1 (BACE1) mediates the first cleavage of the beta-amyloid precursor protein (APP) to yield the… Expand
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The retromer component SNX6 interacts with dynactin p150Glued and mediates endosome-to-TGN transport
The retromer is a protein complex that mediates retrograde transport of transmembrane cargoes from endosomes to the trans-Golgi… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 7
Is this relevant?
Highly Cited
2009
Highly Cited
2009
The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network
Early endosome-to-trans-Golgi network (TGN) transport is organized by the retromer complex. Consisting of cargo-selective and… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2008
2008
An epidermal growth factor (EGF) -dependent interaction between GIT1 and sorting nexin 6 promotes degradation of the EGF receptor.
G-protein coupled receptor (GPCR) kinase-2 interacting protein 1 (GIT1) is a multifunctional scaffolding protein that regulates… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2006
Highly Cited
2006
A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer.
The mammalian retromer is a multimeric protein complex involved in mediating endosome-to-trans-Golgi-network retrograde transport… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.
Sorting nexins (SNX) comprise a family of proteins with homology to several yeast proteins, including Vps5p and Mvp1p, that are… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE