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SMC6 gene

Known as: SMC6, STRUCTURAL MAINTENANCE OF CHROMOSOMES 6, SMC6-LIKE 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Abstract A02: Potential role of SMC6 downregulation as an indicator of tumor genetic instability in breast cancer
Genetic instability is a common feature of cancer. Homologous recombination (HR) is involved in one of the major mechanisms of… 
2017
2017
Genetic evidence for functional interaction of Smc5/6 complex and Top1 with spatial frequency of replication origins required for maintenance of chromosome stability
Replication of linear chromosomes is facilitated by firing of multiple replication origins that ensures timely duplication of the… 
2016
2016
The (elusive) role of the SMC5/6 complex
SMC5/6 is themostmysterious of SMC complexes, as exemplified by the fact that in contrast to SMC1/3 (cohesin) or SMC2/4… 
2016
2016
G2/M chromosome transactions essentially relying on Smc5/6
Smc5/6 is an evolutionarily conserved octameric complex composed of 2 Structural Maintenance of Chromosomes (SMC) subunits (Smc5… 
2015
2015
The Smc5-Smc6 heterodimer associates with DNA through several independent binding domains
The Smc5-6 complex is required for the maintenance of genome integrity through its functions in DNA repair and chromosome… 
Highly Cited
2013
Highly Cited
2013
Dynamic localization of SMC5/6 complex proteins during mammalian meiosis and mitosis suggests functions in distinct chromosome processes
Summary Four members of the structural maintenance of chromosome (SMC) protein family have essential functions in chromosome… 
Review
2009
Review
2009
Foreword: the many fascinating functions of SMC protein complexes
Ever since the first description of mitotic chromosomes by Walther Flemming more than 125 years ago, researchers have been… 
2007
2007
Brc1-Mediated Rescue of Smc5/6 Deficiency: Requirement for Multiple Nucleases and a Novel Rad18 Function
Smc5/6 is a structural maintenance of chromosomes complex, related to the cohesin and condensin complexes. Recent studies… 
2007
2007
Rad50 is involved in MMS-induced recombination between homologous chromosomes in mitotic cells.
The structural maintenance of chromosomes (SMC) family proteins (Smc1-Smc6) typically consist of two coiled-coil domains, an… 
2006
2006
Chromatin loading of Smc5/6 is induced by DNA replication but not by DNA double-strand breaks.
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