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SMC1A gene

Known as: KIAA0178, STRUCTURAL MAINTENANCE OF CHROMOSOMES 1-LIKE 1, Structural Maintenance of Chromosomes 1A Gene 
This gene is involved in maintenance of sister chromatid cohesion during mitosis.
National Institutes of Health

Related topics

Related topics

3 relations
Cell Cycle ControlMitosisStructural Maintenance of Chromosomes Protein 1A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2016
2016
miR-638 suppresses DNA damage repair by targeting SMC1A expression in terminally differentiated cells
The reduction of DNA damage repair capacity in terminally differentiated cells may be involved in sensitivity to cancer… 
2016
2016
Identification of a region in the coiled-coil domain of Smc3 that is essential for cohesin activity
The cohesin complex plays an important role in sister chromatin cohesion. Cohesin's core is composed of two structural… 
2014
2014
Overall and allele-specific expression of the SMC1A gene in female Cornelia de Lange syndrome patients and healthy controls
Cornelia de Lange syndrome (CdLS) is a rare multisystem disorder characterized by facial dysmorphisms, limb anomalies, and growth… 
2010
2010
Interaction between Rae1 and Cohesin subunit SMC1 is required for proper spindle formation
198 Cell Cycle Volume 9 issue 1 We previously reported that Rae1 (RNA export factor 1) interacted with cohesin subunit SMC1… 
2010
2010
Low SMC1A protein expression predicts poor survival in acute myeloid leukemia.
Age is a strong adverse prognostic factor in acute myeloid leukemia. Little is known about the biology of acute myeloid leukemia… 
2010
2010
Cohesin is needed for bipolar mitosis in human cells.
Multi-polar mitosis is strongly linked with aggressive cancers and it is a histological diagnostic of tumor-grade. However… 
2007
2007
Comprehensive mutational analysis of a cohort of Swedish Cornelia de Lange syndrome patients
Cornelia de Lange syndrome (CdLS; OMIM 122470) is a rare multiple congenital anomaly/mental retardation syndrome characterized by… 
1998
1998
Characterization of a supernumerary small marker X chromosome in two females with similar phenotypes.
We describe two female patients mosaic for a cell line with an extra marker X chromosome in addition to a normal 46,XX cell line… 
1995
1995
The DXS423E gene in Xp11.21 escapes X chromosome inactivation.
The DXS423E gene has been localized to Xp11.21 and is expressed in somatic cell hybrids retaining either the human active or… 
1995
1995
The human SB1.8 gene (DXS423E) encodes a putative chromosome segregation protein conserved in lower eukaryotes and prokaryotes.
We report that the human gene SB1.8 (DXS423E) encodes a protein of 1233 amino acids that is highly homologous (30% identity) to… 
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