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SMARCB1 gene

Known as: PPP1R144, SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily B, Member 1 Gene, protein phosphatase 1, regulatory subunit 144 
This gene plays a role in chromatin remodeling and regulation of transcription.
National Institutes of Health

Related topics

Related topics

14 relations
AT/RTChildhood Atypical Teratoid/Rhabdoid TumorExtrarenal Rhabdoid TumorExtrarenal Rhabdoid Tumor of the Liver

Narrower (1)

SMARCB1 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
SMARCB1 Deficiency Integrates Epigenetic Signals to Oncogenic Gene Expression Program Maintenance in Human Acute Myeloid Leukemia
SWI/SNF is an evolutionarily conserved multi-subunit chromatin remodeling complex that regulates epigenetic architecture and… 
2015
2015
Frequent co‐inactivation of the SWI/SNF subunits SMARCB1, SMARCA2 and PBRM1 in malignant rhabdoid tumours
Malignant rhabdoid tumours (MRTs) are highly aggressive malignancies of early infancy characterized by inactivation of SMARCB1, a… 
2014
2014
Premature termination of SMARCB1 translation may be followed by reinitiation in schwannomatosis-associated schwannomas, but results in absence of SMARCB1 expression in rhabdoid tumors
In schwannomatosis, germline SMARCB1 mutations predispose to the development of multiple schwannomas, but not vestibular… 
2014
2014
Coexistent loss of INI1 and BRG1 expression in a rhabdoid renal cell carcinoma (RCC): implications for a possible role of SWI/SNF complex in the pathogenesis of RCC.
In this study, we analyzed the immunohistochemical and molecular profiles of an unusual RCC showed coexistent absence of INI1 and… 
2014
2014
SMARCB1 Involvement in the Development of Leiomyoma in a Patient With Schwannomatosis
Germline SMARCB1 mutations predispose in schwannomatosis patients to the development of multiple benign schwannomas and, in some… 
Review
2012
Review
2012
High-grade carcinomas involving the renal sinus: report of a case and review of the differential diagnosis and immunohistochemical expression.
We report the case of a high-grade carcinoma involving the kidney in a young male with renal vein thrombosis and review the… 
Highly Cited
2003
Highly Cited
2003
INI1 expression induces cell cycle arrest and markers of senescence in malignant rhabdoid tumor cells
The INI1 gene, which encodes a functionally uncharacterized protein component of the hSWI/SNF chromatin remodeling complex, is… 
2003
2003
The Drosophila SNR1 (SNF5/INI1) Subunit Directs Essential Developmental Functions of the Brahma Chromatin Remodeling Complex
ABSTRACT The Drosophila melanogaster Brahma (Brm) complex, a counterpart of the Saccharomyces cerevisiae SWI/SNF ATP-dependent… 
2000
2000
Inactivation of the SNF5 transcription factor gene abolishes the lethal phenotype induced by the expression of HIV-1 integrase in yeast.
1999
1999
The mouse ortholog of the human SMARCB1 gene encodes two splice forms.
The human SMARCB1 gene (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily b, member 1… 
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