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ABSTRACT Mutation of BRG1, hBRM, and their associated factors, INI1 and BAF57, in primary human tumors has suggested that… Expand ABSTRACT Protein arginine methyltransferases (PRMTs) have been implicated in transcriptional activation and repression, but their… Expand The androgen receptor (AR) is a ligand-dependent transcription factor whose activity is required for prostate cancer… Expand Alteration of nucleosomes by ATP-dependent remodeling complexes represents a critical step in the regulation of transcription… Expand Forced expression of the retinoblastoma (RB) gene product inhibits the proliferation of cells in culture. A major target of the… Expand The human SNF2alpha (or hbrm) and SNF2beta (or BRG1) proteins have previously been shown to enhance transcriptional activation by… Expand hBRG1 and hBRM are mammalian homologs of the SNF2/SW12 yeast transcriptional activator. These proteins exist in a large… Expand In yeast, the SNF/SWI complex is believed to regulate transcription by locally altering the chromatin structure. At the present… Expand THE Saccharomyces cerevisiae SNF2/SWI2 protein is essential for the regulated expression of a variety of genes1,2. A human SW12… Expand Several of the SNF and SWI genes of Saccharomyces cerevisiae code for proteins believed to assist transcriptional activators by… Expand