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SLIT2 gene

Known as: SLIT, DROSOPHILA, HOMOLOG OF, 2, SLIT2, slit guidance ligand 2 
This gene is involved in cell migration and nervous system development.
National Institutes of Health

Related topics

Related topics

9 relations
Angiogenic ProcessChemotaxis InhibitionNeurogenesisSLIT2 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Overexpression of Slit2 improves function of the paravascular pathway in the aging mouse brain
Aging is associated with impairment of the paravascular pathway caused by the activation of astrocytes and depolarization of… 
2016
2016
Expression, clinical significance and mechanism of Slit2 in papillary thyroid cancer.
Thyroid cancer is a common endocrine malignancy. The last decade has seen exciting progress in understanding thyroid cancer… 
2015
2015
Nkx2.1-derived astrocytes and neurons together with Slit2 are indispensable for anterior commissure formation
Guidepost cells present at and surrounding the midline provide guidance cues that orient the growing axons through commissures… 
2015
2015
miR-1179 promotes cell invasion through SLIT2/ROBO1 axis in esophageal squamous cell carcinoma.
MiR-1179, a new identified miRNA highly associated with metastasis of colorectal cancer which was never reported in esophageal… 
2013
2013
Isoflurane post-conditioning protects primary cultures of cortical neurons against oxygen and glucose deprivation injury via upregulation of Slit2/Robo1
2012
2012
The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis.
2012
2012
Inactivation of SLIT2-ROBO1/2 Pathway in Premalignant Lesions of Uterine Cervix: Clinical and Prognostic Significances
The SLIT2-ROBO1/2 pathways control diverse biological processes, including growth regulation. To understand the role of SLIT2 and… 
2012
2012
Slit2 Inactivates GSK3β to Signal Neurite Outgrowth Inhibition
Slit molecules comprise one of the four canonical families of axon guidance cues that steer the growth cone in the developing… 
2011
2011
Detection of Slit2 promoter hypermethylation in tissue and serum samples from breast cancer patients
Promoter hypermethylation has been shown to be a common mechanism for inactivation of tumor suppressor genes in breast cancer… 
2011
2011
A novel exon 15‐deleted, splicing variant of Slit2 shows potential for growth inhibition in addition to invasion inhibition in lung cancer
The axon guidance cue molecule Slit2 has been shown to suppress cancer cell invasion. However, the role of Slit2 in growth… 
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