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SLC9A9 wt Allele

Known as: NHE9, Solute Carrier Family 9 (Sodium/Hydrogen Exchanger), Isoform 9 Gene, FLJ35613 
Human SLC9A9 wild-type allele is located in the vicinity of 3q24 and is approximately 583 kb in length. This allele, which encodes sodium/hydrogen… 
National Institutes of Health

Related topics

Related topics

7 relations
3q24Acid-Base EquilibriumHomo sapiensIonophore activity

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
New trends in glioma cancer therapy: Targeting Na+/H + exchangers
Glioma is the oneof the most prevalent primarybrain tumors. There is a variety of oxidative stresses, inflammatory pathways… 
2019
2019
A gain of function paradox: Targeted therapy for glioblastoma associated with abnormal NHE9 expression
Glioblastoma (GBM) is the most frequent and inevitably lethal primary brain cancer in adults. It is recognized that the… 
2018
2018
A mouse model of autism implicates endosome pH in the regulation of presynaptic calcium entry
Psychoactive compounds such as chloroquine and amphetamine act by dissipating the pH gradient across intracellular membranes, but… 
2017
2017
Na+/H+ Exchanger 9 Regulates Iron Mobilization at the Blood-Brain Barrier in Response to Iron Starvation*
Iron is essential for brain function, with loss of iron homeostasis in the brain linked to neurological diseases ranging from… 
Review
2016
Review
2016
Emerging roles of Na+/H+ exchangers in epilepsy and developmental brain disorders
2014
2014
The intracellular Na(+)/H(+) exchanger NHE7 effects a Na(+)-coupled, but not K(+)-coupled proton-loading mechanism in endocytosis.
Highly Cited
2013
Highly Cited
2013
Genes for endosomal NHE6 and NHE9 are misregulated in autism brains
Autism is a highly heterogeneous neurodevelopmental disorder with impaired language, social communication, and restricted and… 
Highly Cited
2013
Highly Cited
2013
FUNCTIONAL EVALUATION OF AUTISM-ASSOCIATED MUTATIONS IN NHE9
NHE9 (SLC9A9) is an endosomal cation/proton antiporter with orthologues in yeast and bacteria. Rare, missense substitutions in… 
2013
2013
Nhe6 and Nhe9 are sodium hydrogen exchangers found on separate mobile endosome populations in neuronal dendrites
This dissertation reports the endosomal locations of NHE6 and NHE9, sodium hydrogen exchangers that contribute to pathogenesis of… 
Highly Cited
2006
Highly Cited
2006
Vestibular Hair Bundles Control pH with (Na+, K+)/H+ Exchangers NHE6 and NHE9
In hair cells of the inner ear, robust Ca2+/H+ exchange mediated by plasma-membrane Ca2+-ATPase would rapidly acidify… 
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