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The apical sodium-dependent bile acid transporter (Asbt) is responsible for transport across the intestinal brush border membrane… Expand Mice deficient in the organic solute transporter (Ost)-alpha subunit of the heteromeric organic solute and steroid transporter… Expand Activation of the pregnane X receptor (PXR) has been shown to protect against cholestatic hepatotoxicity. As PXR alters the… Expand Using cytokeratin-7-positive trophoblast cells (hTr) isolated from human term placentas and the choriocarcinoma cell lines (hCC… Expand Cholangiocytes are exposed to high concentrations of bile acids at their apical membrane. A selective transporter for bile acids… Expand Organic solute transporter (OSTalpha-OSTbeta) is a novel heteromeric bile acid and sterol transporter expressed at the… Expand Expression of the farnesoid X receptor (FXR; NR1H4) is limited to the liver, intestine, kidney, and adrenal gland. However, the… Expand Bile acids are transported across the ileal enterocyte brush border membrane by the well characterized apical sodium-dependent… Expand These studies identify an organic solute transporter (OST) that is generated when two novel gene products are co-expressed… Expand In Gram‐negative bacteria, all components of the outer membrane are synthesized in the cytoplasm or the cytoplasmic leaflet of… Expand