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SLC48A1 gene

Known as: FLJ20489, SLC48A1, hHRG-1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Hemozoin produced by mammals confers heme tolerance
Free heme is cytotoxic as exemplified by hemolytic diseases and genetic deficiencies in heme recycling and detoxifying pathways… 
2016
2016
MRTF/SRF dependent transcriptional regulation of TAZ in breast cancer cells
Dysregulation of Hippo pathway results in activation of transcriptional co-activators YAP/TAZ in breast cancer. Previously, we… 
Highly Cited
2013
Highly Cited
2013
HRG1 is essential for heme transport from the phagolysosome of macrophages during erythrophagocytosis.
Review
2013
Review
2013
Heme and FLVCR-related transporter families SLC48 and SLC49.
Highly Cited
2013
Highly Cited
2013
Novel Hematopoietic Target Genes in the NRF2-Mediated Transcriptional Pathway
Nuclear factor- (erythroid-derived 2) like 2 (NFE2L2, NRF2) is a key transcriptional activator of the antioxidant response… 
Highly Cited
2011
Highly Cited
2011
Topologically Conserved Residues Direct Heme Transport in HRG-1-related Proteins*
Background: HRG-1-related proteins have low sequence homology but are functionally conserved. Results: Conserved residues within… 
2011
2011
Use of Stringent Selection Parameters for the Identification of Possible Selenium-Responsive Marker Genes in Mouse Liver and Gastrocnemius
Selenium is a trace element that, although toxic in higher concentrations, is essential for human and animal health. In this… 
2006
2006
Heregulins Implicated in Cellular Functions Other Than Receptor Activation
Heregulins (HRG) are known as soluble secreted growth factors that, on binding and activating ErbB3 and ErbB4 cell surface… 
2006
2006
The epidermal growth factor family has a dual role in deciding the fate of cancer cells
Expression of the epidermal growth factor (EGF) receptors HER1 and HER2 has been implicated in tumour growth and poor survival… 
Highly Cited
2002
Highly Cited
2002
The breast proto-oncogene, HRGα regulates epithelial proliferation and lobuloalveolar development in the mouse mammary gland
Members of the EGF family of growth factors play critical roles during normal and neoplastic breast development. EGF family… 
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