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SLC22A13 gene

Known as: OCTL3, OAT10, ORCTL3 
National Institutes of Health

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SLC22A10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Recent approaches to gout drug discovery: an update
ABSTRACT Introduction Inflammation induced by urate deposition in joints causes gout. Healthy individuals maintain serum levels… 
2020
2020
The mechanism of Arhalofenate in alleviating hyperuricemia―Activating PPARγ thereby reducing caspase‐1 activity
Hyperuricemia (HUA) is an important risk factor for renal diseases and contributes to gout. Arhalofenate (Arha) has been proved… 
Review
2018
Review
2018
The systems biology of uric acid transporters: the role of remote sensing and signaling
Purpose of review Uric acid homeostasis in the body is mediated by a number of SLC and ABC transporters in the kidney and… 
Highly Cited
2016
Highly Cited
2016
Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling
Background In the setting of chronic kidney disease (CKD), altered extra-renal urate handling may be necessary to regulate plasma… 
2016
2016
Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography.
2014
2014
SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct.
In vertebrates, SLC22A13 is an evolutionarily conserved transport protein of the plasma membrane. In humans and rat, it is… 
2014
2014
The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis
ORCTL3 is a member of a group of genes, the so-called anticancer genes, that cause tumour-specific cell death. We show that this… 
2013
2013
FRI0403 Arhalofenate, a novel uricosuric agent, is an inhibitor of human URIC acid transporters
Background It is estimated that the hyperuricemia in 80- 90% of gout patients is due to under excretion of uric acid. Uricouric… 
Review
2011
Review
2011
In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy.
Organic anion transporters 1-10 (OAT1-10) and the urate transporter 1 (URAT1) belong to the SLC22A gene family and accept a huge… 
2007
2007
Identification of a kidney-specific mouse organic cation transporter like-1 (mOCTL1)
Organic ion transporters are expressed in various tissues that transport endogenous and exogenous compounds including their… 
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