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SLC22A13 gene
Known as:
OCTL3
, OAT10
, ORCTL3
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National Institutes of Health
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1 relation
SLC22A10 gene
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Recent approaches to gout drug discovery: an update
N. Otani
,
M. Ouchi
,
Hideo Kudo
,
S. Tsuruoka
,
I. Hisatome
,
N. Anzai
Expert Opinion on Drug Discovery
2020
Corpus ID: 216110716
ABSTRACT Introduction Inflammation induced by urate deposition in joints causes gout. Healthy individuals maintain serum levels…
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2020
2020
The mechanism of Arhalofenate in alleviating hyperuricemia―Activating PPARγ thereby reducing caspase‐1 activity
Gui-Hong Wang
,
T. Zuo
,
Ran Li
Drug development research (Print)
2020
Corpus ID: 219536462
Hyperuricemia (HUA) is an important risk factor for renal diseases and contributes to gout. Arhalofenate (Arha) has been proved…
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Review
2018
Review
2018
The systems biology of uric acid transporters: the role of remote sensing and signaling
S. Nigam
,
V. Bhatnagar
Current opinion in nephrology and hypertension
2018
Corpus ID: 44089235
Purpose of review Uric acid homeostasis in the body is mediated by a number of SLC and ABC transporters in the kidney and…
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Highly Cited
2016
Highly Cited
2016
Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling
V. Bhatnagar
,
E. Richard
,
+5 authors
S. Nigam
Clinical Kidney Journal
2016
Corpus ID: 17591031
Background In the setting of chronic kidney disease (CKD), altered extra-renal urate handling may be necessary to regulate plasma…
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2016
2016
Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography.
Ling Wei
,
H. Tominaga
,
+8 authors
Y. Kanai
Journal of Pharmacological Sciences
2016
Corpus ID: 10593966
2014
2014
SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct.
Christian Schulz
,
Christian Fork
,
+4 authors
D. Gründemann
Biochemical Journal
2014
Corpus ID: 25553055
In vertebrates, SLC22A13 is an evolutionarily conserved transport protein of the plasma membrane. In humans and rat, it is…
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2014
2014
The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis
G. Abuali
,
W. Chaisaklert
,
+10 authors
S. Grimm
Oncogene
2014
Corpus ID: 13120219
ORCTL3 is a member of a group of genes, the so-called anticancer genes, that cause tumour-specific cell death. We show that this…
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2013
2013
FRI0403 Arhalofenate, a novel uricosuric agent, is an inhibitor of human URIC acid transporters
B. Lavan
,
C. Mcwherter
,
Y. Choi
2013
Corpus ID: 58984976
Background It is estimated that the hyperuricemia in 80- 90% of gout patients is due to under excretion of uric acid. Uricouric…
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Review
2011
Review
2011
In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy.
G. Burckhardt
,
B. Burckhardt
Handbook of Experimental Pharmacology
2011
Corpus ID: 35002382
Organic anion transporters 1-10 (OAT1-10) and the urate transporter 1 (URAT1) belong to the SLC22A gene family and accept a huge…
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2007
2007
Identification of a kidney-specific mouse organic cation transporter like-1 (mOCTL1)
W. Lee
,
Ji‐Sun Hwang
,
C. Yun
,
S. Cha
Experimental and Molecular Medicine
2007
Corpus ID: 23950699
Organic ion transporters are expressed in various tissues that transport endogenous and exogenous compounds including their…
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