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SLC22A13 gene

Known as: OCTL3, OAT10, ORCTL3 
 
National Institutes of Health

Related topics

Related topics

1 relation
SLC22A10 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Recent approaches to gout drug discovery: an update.
Introduction: Inflammation induced by urate deposition in joints causes gout. Healthy individuals maintain serum levels of urate… Expand
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2020
2020
The mechanism of Arhalofenate in alleviating hyperuricemia-Activating PPARγ thereby reducing caspase-1 activity.
Hyperuricemia (HUA) is an important risk factor for renal diseases and contributes to gout. Arhalofenate (Arha) has been proved… Expand
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2016
2016
Analysis of ABCG2 and other urate transporters in uric acid homeostasis in chronic kidney disease: potential role of remote sensing and signaling
Background In the setting of chronic kidney disease (CKD), altered extra-renal urate handling may be necessary to regulate plasma… Expand
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2016
2016
Transport of 3-fluoro-L-α-methyl-tyrosine (FAMT) by organic ion transporters explains renal background in [(18)F]FAMT positron emission tomography.
A PET tracer for tumor imaging, 3-(18)F-l-α-methyl-tyrosine ([(18)F]FAMT), has advantages of high cancer-specificity and low… Expand
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2015
2015
The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis
ORCTL3 is a member of a group of genes, the so-called anticancer genes, that cause tumour-specific cell death. We show that this… Expand
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2014
2014
SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct.
In vertebrates, SLC22A13 is an evolutionarily conserved transport protein of the plasma membrane. In humans and rat, it is… Expand
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2013
2013
FRI0403 Arhalofenate, a novel uricosuric agent, is an inhibitor of human URIC acid transporters
Background It is estimated that the hyperuricemia in 80- 90% of gout patients is due to under excretion of uric acid. Uricouric… Expand
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Review
2011
Review
2011
In vitro and in vivo evidence of the importance of organic anion transporters (OATs) in drug therapy.
Organic anion transporters 1-10 (OAT1-10) and the urate transporter 1 (URAT1) belong to the SLC22A gene family and accept a huge… Expand
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2009
2009
Die Transporter SLC22A7 (OAT2) und SLC22A13: Substratsuche, Lokalisation, Entdeckung eines Orotsäure-Transporters
Die Solute Carrier SLC22A7 (OAT2, "Organic Anion Transporter 2") und SLC22A13 liegen in mehreren Mammalia-Spezies konserviert vor… Expand
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2007
2007
Identification of a kidney-specific mouse organic cation transporter like-1 (mOCTL1)
Organic ion transporters are expressed in various tissues that transport endogenous and exogenous compounds including their… Expand
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