Skip to search formSkip to main contentSkip to account menu

SLAMF7 protein, human

Known as: CD2 Subset 1, SLAM family member 7 protein, human, CRACC protein, human 
SLAM family member 7 (335 aa, ~37 kDa) is encoded by the human SLAMF7 gene. This protein is involved in signal transduction that promotes the… 
National Institutes of Health

Related topics

Related topics

7 relations
Immunoglobulin C2-set DomainNK Cell ActivationSLAMF7 geneSLAMF7 wt Allele

Broader (1)

Signaling Lymphocytic Activation Molecule Family

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Profile of elotuzumab and its potential in the treatment of multiple myeloma
Although the introduction of novel drugs has improved outcome significantly in multiple myeloma (MM), many patients still… 
2013
2013
Systemic Lupus Erythematosus Immune Complexes Increase the Expression of SLAM Family Members CD319 (CRACC) and CD229 (LY-9) on Plasmacytoid Dendritic Cells and CD319 on CD56dim NK Cells
Patients with systemic lupus erythematosus (SLE) display an activated type I IFN system due to unceasing IFN-α release from… 
2012
2012
Quantitative colorimetric measurement of cellulose degradation under microbial culture conditions
We have developed a simple, rapid, quantitative colorimetric assay to measure cellulose degradation based on the absorbance shift… 
2011
2011
Overexpression of EAT-2, a SLAM family receptor adaptor molecule, suppresses CRACC receptor expression on Antigen Presenting Cells in an ERK MAP kinase dependent mechanism (110.26)
SLAM family receptors play a critical role in immune regulation. Their function is controlled primarily by SAP, EAT-2, and ERT… 
Highly Cited
2009
Highly Cited
2009
Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function
CRACC is a self-associating member of the signaling lymphocytic activation molecule family that is expressed on cells of the… 
2007
2007
This information is current as Human B Lymphocytes and Autocrine Cytokine Expression on CS 1 ( CRACC , CD 319 ) Induces Proliferation
Highly Cited
2006
Highly Cited
2006
2B4 (CD244), NTB-A and CRACC (CS1) stimulate cytotoxicity but no proliferation in human NK cells.
The recently described family of SLAM-related receptors plays an important role in the modulation of lymphocyte activity. The… 
2005
2005
Human NK Cells Signaling Pathways in g Phospholipase C Recruits EAT-2 and Activates the PI3K and The Cytotoxicity Receptor CRACC (CS-1)
The CD2-like receptor-activating cytotoxic cell (CRACC) is a cell surface receptor of the CD2 family that triggers NK cell… 
2004
2004
Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine‐based switch motifs
CS1 (CRACC, novel Ly9) is a novel member of the CD2 family expressed on natural killer (NK), T and stimulated B cells. Although… 
Highly Cited
2003
Highly Cited
2003
Functional Requirements for Interactions Between CD84 and Src Homology 2 Domain-Containing Proteins and Their Contribution to Human T Cell Activation 1
Cell surface receptors belonging to the CD2 subset of the Ig superfamily of molecules include CD2, CD48, CD58, 2B4, signaling… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)