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SKIL gene
Known as:
SKI-like proto-oncogene
, SKIL
, SKI-LIKE
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This gene plays a role in signal transduction. It is involved in regulating whether cells undergo differentiation or division.
National Institutes of Health
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Related topics
Related topics
5 relations
Cell Proliferation Regulatory Process
SKIL protein, human
Signal Transduction
Transcriptional Regulation
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1*
Y. Ikeuchi
,
S. Dadakhujaev
,
+8 authors
S. Bonni
Journal of Biological Chemistry
2014
Corpus ID: 23444368
Background: Epithelial-mesenchymal transition (EMT) plays critical roles in tissue development and cancer biology. Results: TIF1…
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2013
2013
Expression Profiles of SnoN in Normal and Cancerous Human Tissues Support Its Tumor Suppressor Role in Human Cancer
N. Jahchan
,
G. Ouyang
,
K. Luo
PLoS ONE
2013
Corpus ID: 12414957
SnoN is a negative regulator of TGF-β signaling and also an activator of the tumor suppressor p53 in response to cellular stress…
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2013
2013
SnoN/SkiL expression is modulated via arsenic trioxide‐induced activation of the PI3K/AKT pathway in ovarian cancer cells
Karthik M. Kodigepalli
,
Punashi Dutta
,
K. Bauckman
,
M. Nanjundan
FEBS Letters
2013
Corpus ID: 46243961
2011
2011
Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression
D. Javelaud
,
L. V. van Kempen
,
V. Alexaki
,
Erwan Le Scolan
,
K. Luo
,
A. Mauviel
Molecular Cancer
2011
Corpus ID: 14668790
BackgroundSKI and SnoN proteins have been shown to inhibit TGF-β signaling, acting both as transcriptional co-repressors in the…
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2008
2008
TGF-β Repressors SnoN and Ski Are Implicated in Human Colorectal Carcinogenesis
V. Bravou
,
A. Antonacopoulou
,
+5 authors
H. Kalofonos
Cellular Oncology
2008
Corpus ID: 18739379
Background: The TGF-β signaling repressors SnoN and Ski have been critically implicated in human cancer. Methods: To explore the…
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Review
2008
Review
2008
SnoN in TGF-beta signaling and cancer biology.
I. Pot
,
S. Bonni
Current molecular medicine
2008
Corpus ID: 40682544
The Transforming Growth Factor (TGF)- beta-Smad signaling pathway regulates diverse biological processes essential for normal…
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2007
2007
Transforming Growth Factor-β-independent Regulation of Myogenesis by SnoN Sumoylation*
Katharine H. Wrighton
,
M. Liang
,
+4 authors
Xia Lin
Journal of Biological Chemistry
2007
Corpus ID: 25001739
Recent progress has been made on the role of oncoproteins c-Ski and related SnoN in the control of cellular transformation. c-Ski…
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Highly Cited
2006
Highly Cited
2006
Sumoylated SnoN Represses Transcription in a Promoter-specific Manner*
Y. R. Hsu
,
K. Sarker
,
I. Pot
,
A. Chan
,
S. Netherton
,
S. Bonni
Journal of Biological Chemistry
2006
Corpus ID: 39322455
The transcriptional modulator SnoN controls a diverse set of biological processes, including cell proliferation and…
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2003
2003
Two Short Segments of Smad3 Are Important for Specific Interaction of Smad3 with c-Ski and SnoN* 210
M. Mizuide
,
T. Hara
,
+7 authors
K. Miyazono
Journal of Biological Chemistry
2003
Corpus ID: 39362578
c-Ski and SnoN are transcriptional co-repressors that inhibit transforming growth factor-β signaling through interaction with…
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2002
2002
Inhibition of premixed methane flames by manganese and tin compounds Official contribution of NI
G. Linteris
,
V. D. Knyazev
,
V. Babushok
2002
Corpus ID: 55910160
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