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SKIL gene

Known as: SKI-like proto-oncogene, SKIL, SKI-LIKE 
This gene plays a role in signal transduction. It is involved in regulating whether cells undergo differentiation or division.
National Institutes of Health

Related topics

Related topics

5 relations
Cell Proliferation Regulatory ProcessSKIL protein, humanSignal TransductionTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
TIF1γ Protein Regulates Epithelial-Mesenchymal Transition by Operating as a Small Ubiquitin-like Modifier (SUMO) E3 Ligase for the Transcriptional Regulator SnoN1*
Background: Epithelial-mesenchymal transition (EMT) plays critical roles in tissue development and cancer biology. Results: TIF1… 
2013
2013
Expression Profiles of SnoN in Normal and Cancerous Human Tissues Support Its Tumor Suppressor Role in Human Cancer
SnoN is a negative regulator of TGF-β signaling and also an activator of the tumor suppressor p53 in response to cellular stress… 
2013
2013
SnoN/SkiL expression is modulated via arsenic trioxide‐induced activation of the PI3K/AKT pathway in ovarian cancer cells
2011
2011
Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression
BackgroundSKI and SnoN proteins have been shown to inhibit TGF-β signaling, acting both as transcriptional co-repressors in the… 
2008
2008
TGF-β Repressors SnoN and Ski Are Implicated in Human Colorectal Carcinogenesis
Background: The TGF-β signaling repressors SnoN and Ski have been critically implicated in human cancer. Methods: To explore the… 
Review
2008
Review
2008
SnoN in TGF-beta signaling and cancer biology.
The Transforming Growth Factor (TGF)- beta-Smad signaling pathway regulates diverse biological processes essential for normal… 
2007
2007
Transforming Growth Factor-β-independent Regulation of Myogenesis by SnoN Sumoylation*
Recent progress has been made on the role of oncoproteins c-Ski and related SnoN in the control of cellular transformation. c-Ski… 
Highly Cited
2006
Highly Cited
2006
Sumoylated SnoN Represses Transcription in a Promoter-specific Manner*
The transcriptional modulator SnoN controls a diverse set of biological processes, including cell proliferation and… 
2003
2003
Two Short Segments of Smad3 Are Important for Specific Interaction of Smad3 with c-Ski and SnoN* 210
c-Ski and SnoN are transcriptional co-repressors that inhibit transforming growth factor-β signaling through interaction with… 
2002
2002
Inhibition of premixed methane flames by manganese and tin compounds Official contribution of NI
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