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SK 3541

Known as: SK-3541, SK3541 
National Institutes of Health

Papers overview

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2010
2010
Pharmacokinetics of mirodenafil and its two metabolites, SK3541 and SK3544, after intravenous and oral administration of mirodenafil to streptozotocin-induced diabetes mellitus rats
The area under the curve (AUC) of mirodenafil after intravenous administration in diabetes mellitus induced by streptozotocin… 
2010
2010
Pharmacokinetics of mirodenafil, a new erectogenic, and its metabolite, SK3541, in rats: involvement of CYP1A1/2, 2B1/2, 2D subfamily, and 3A1/2 for the metabolism of both mirodenafil and SK3541.
PURPOSE This study was performed to find which types of hepatic CYP isoforms are responsible for the metabolism of mirodenafil (a… 
2009
2009
Dose‐dependent pharmacokinetics and first‐pass effects of mirodenafil, a new erectogenic, in rats
The pharmacokinetics of mirodenafil and its two metabolites, SK3541 and SK3544, after intravenous (5, 10, 20 and 50 mg/kg) and… 
2009
2009
Faster clearance of mirodenafil in rats with acute renal failure induced by uranyl nitrate: contribution of increased protein expression of hepatic CYP3A1 and intestinal CYP1A1 and 3A1/2.
OBJECTIVES It has been reported that mirodenafil is primarily metabolized via hepatic cytochrome P450 (CYP) 1A1/2, 2B1/2, 2D1 and… 
2007
2007
Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human…
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