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SK&F 29661
Known as:
SK&F-29661
, SKF 29661
, SKF-29661
National Institutes of Health
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Semantic Scholar uses AI to extract papers important to this topic.
2004
2004
Studies on the long term effects of SK&F 29661 upon adrenal catecholamines
R. Pendleton
,
G. Gessner
,
J. Sawyer
,
L. Hillegass
,
D. Miller
Naunyn-Schmiedeberg's Archives of Pharmacology
2004
Corpus ID: 23045636
SummarySK&F 29661 (1,2,3,4-tetrahydro-7-isoquinoline-sulfonamide) is a potent and selective in vitro and in vivo inhibitor of…
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1997
1997
Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK&F 29661) toward inhibition of phenylethanolamine N-methyltransferase vs…
G. L. Grunewald
,
V. Dahanukar
,
T. Caldwell
,
K. R. Criscione
Journal of medicinal chemistry
1997
Corpus ID: 5757856
7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK&F 29661, 1) is a potent inhibitor of the enzyme phenylethanolamine N…
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1993
1993
Glucocorticoid hypertension and nonadrenal phenylethanolamine N-methyltransferase.
B. Kennedy
,
H. Elayan
,
M. Ziegler
Hypertension
1993
Corpus ID: 15766068
Several drugs that block epinephrine synthesis by inhibiting phenylethanolamine N-methyltransferase (PNMT) lower blood pressure…
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1991
1991
Epinephrine synthesis by rat arteries.
B. Kennedy
,
H. Elayan
,
M. Ziegler
American journal of hypertension
1991
Corpus ID: 20303543
Carotid artery and aorta homogenates synthesized epinephrine (E) from norepinephrine (NE) in the presence of S-adenosylmethionine…
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1990
1990
Cardiac atria and ventricles contain different inducible adrenaline synthesising enzymes.
H. Elayan
,
B. Kennedy
,
M. Ziegler
Cardiovascular research
1990
Corpus ID: 28984504
STUDY OBJECTIVE - The aim of the study was to investigate adrenaline synthesis in atrial and ventricular homogenates. DESIGN…
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1990
1990
Lung epinephrine synthesis.
B. Kennedy
,
H. Elayan
,
M. Ziegler
The American journal of physiology
1990
Corpus ID: 6546296
We studied in vitro and in vivo epinephrine (E) synthesis by rat lung. Nine days after removal of the adrenal medullas…
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1986
1986
Effects of various inhibitors of phenylethanolamine N-methyltransferase on pulsatile release of LH in ovariectomized rats.
C. Coen
,
R. Gallo
The Journal of endocrinology
1986
Corpus ID: 23371285
This study was undertaken to investigate whether hypothalamic adrenaline is involved in pulsatile LH release in rats. Various…
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1984
1984
[Adrenal epinephrine and the regulation of pulmonary surfactant release in neonatal rabbits].
J. Padbury
,
H. Jacobs
,
R. Lam
,
D. Conaway
,
A. Jobe
,
D. Fisher
Experimental lung research
1984
Corpus ID: 36318936
Adrenergic mechanisms influence surfactant metabolism; however the nature and importance of catechol-mediated regulation is…
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1980
1980
The effects of PNMT inhibitors upon cardiovascular changes induced by hemorrhage in the rat.
R. Pendleton
,
J. Mccafferty
,
J. Roesler
European journal of pharmacology
1980
Corpus ID: 35605101
1979
1979
Studies on SK&F 29661, an organ-specific inhibitor of phenylethanolamine N-methyltransferase.
R. Pendleton
,
G. Gessner
,
+4 authors
A. Intoccia
The Journal of pharmacology and experimental…
1979
Corpus ID: 21521845
SK&F 29661 is an effective, reversible inhibitor of both central nervous system and adrenal phenylethanolamine N-methyl…
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