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SK&F 29661

Known as: SK&F-29661, SKF 29661, SKF-29661 
National Institutes of Health

Papers overview

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1997
1997
Examination of the role of the acidic hydrogen in imparting selectivity of 7-(aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK&F 29661) toward inhibition of phenylethanolamine N-methyltransferase vs…
7-(Aminosulfonyl)-1,2,3,4-tetrahydroisoquinoline (SK&F 29661, 1) is a potent inhibitor of the enzyme phenylethanolamine N… 
1993
1993
Glucocorticoid hypertension and nonadrenal phenylethanolamine N-methyltransferase.
Several drugs that block epinephrine synthesis by inhibiting phenylethanolamine N-methyltransferase (PNMT) lower blood pressure… 
1991
1991
Epinephrine synthesis by rat arteries.
Carotid artery and aorta homogenates synthesized epinephrine (E) from norepinephrine (NE) in the presence of S-adenosylmethionine… 
1990
1990
Lung epinephrine synthesis.
We studied in vitro and in vivo epinephrine (E) synthesis by rat lung. Nine days after removal of the adrenal medullas… 
1990
1990
Epinephrine synthesis in the rat iris.
Epinephrine (E) alters blood flow, intraocular pressure and pupillary constriction. The rat iris contained E-forming activity… 
1989
1989
Inhibition of guinea pig lordosis behavior by the phenylethanolamine N-methyltransferase (PNMT) inhibitor SKF-64139: Mediation by α noradrenergic receptors
1986
1986
Effects of various inhibitors of phenylethanolamine N-methyltransferase on pulsatile release of LH in ovariectomized rats.
This study was undertaken to investigate whether hypothalamic adrenaline is involved in pulsatile LH release in rats. Various… 
1984
1984
[Adrenal epinephrine and the regulation of pulmonary surfactant release in neonatal rabbits].
Adrenergic mechanisms influence surfactant metabolism; however the nature and importance of catechol-mediated regulation is… 
1981
1981
Blood Pressure Response to Central and /or Peripheral Inhibition of Phenylethanolamine N‐Methyltransferase in Normotensive and Hypertensive Rats
We studied the effects on blood pressure and heart rate of two different phenylethanolamine JV-methyltransferase (PNMT… 
1980
1980
The effects of PNMT inhibitors upon cardiovascular changes induced by hemorrhage in the rat.
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