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SK&F 105494

Known as: SK&F-105494, SKF 105,494 
 
National Institutes of Health

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2 relations

Broader (1)

Argipressin
analogs & derivatives

Papers overview

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Review
1998
Review
1998
VPA-985, a nonpeptide orally active and selective vasopressin V2 receptor antagonist.
The introduction of the thiazides as orally-active diuretics about forty years ago (1), and other more effective low-ceiling… Expand
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1996
1996
SK&F 105494, a V2-vasopressin receptor antagonist, blocks oxytocin receptors in porcine myometrium.
  • H. Yu, W. Hsu
  • Zhongguo yao li xue bao = Acta pharmacologica…
  • 1996
    • Corpus ID: 7888784
AIM To study the effects of SK & F 105494 (SK & F), a V2-vasopressin receptor antagonist, on lypressin (Lyp)- and oxytocin (Oxy… Expand
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1992
1992
Vasopressin antagonist inhibition of clotting factor release in the rhesus monkey (Macaca mulatta).
The antidiuretic (V2) agonist, dDAVP, stimulates release of the clotting factors von Willebrand factor (vWF) and factor VIIIc… Expand
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1991
1991
The water diuretic effect of the alpha-2 adrenoceptor agonist, AGN 190851, is species-dependent.
The effect of the novel alpha-2 adrenoceptor agonist, AGN 190851, was evaluated for its diuretic action in the rat, dog and… Expand
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1990
1990
Effect of cyclo‐oxygenase blockade on the renal actions of vasopressin and SK&F 105494 in the rhesus monkey
1 Vasopressin administration to pentobarbitone‐anaesthetized, hydrated female rhesus monkeys resulted in dose‐dependent increases… Expand
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1990
1990
High-performance liquid chromatographic determination of an arginine-containing octapeptide antagonist of vasopressin in human plasma by means of a selective post-column reaction with fluorescence…
A novel high-performance liquid chromatographic method was developed for the determination in plasma samples of the synthetic… Expand
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1989
1989
Noncyclic vasopressin analogs are effective diuretics in conscious rats.
Linear vasopressin analogs lacking a cyclic hexapeptide ring have recently been reported to possess vasopressin antagonist… Expand
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1989
1989
Cyclooxygenase inhibition unmasks the full antidiuretic agonist activity of the vasopressin antagonist, SK&F 101926, in dogs.
The vasopressin (AVP) antagonist, SK&F 101926 (beta-mercapto-beta beta-cyclopentamethylene propionic acid1, D-Tyr(Et)2, Phe3… Expand
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1988
1988
SK&F 105494 is a potent antidiuretic hormone antagonist in the rhesus monkey (Macaca mulatta).
The vasopressin analog desGly(CH2)5D-Tyr(Et)VAVP (SK&F 101926) is a potent antagonist of the antidiuretic action of vasopressin… Expand
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1988
1988
SK&F 105494: a potent antidiuretic hormone antagonist devoid of partial agonist activity in dogs.
Previous studies from our laboratory have shown that in vivo cyclooxygenase blockade in dogs unmasks the antidiuretic agonist… Expand
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