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SIPA-1 Protein

Known as: GTPase-Activating Protein SPA-1, P130 SPA-1, Signal-Induced Proliferation-Associated Protein 1 
Signal-induced proliferation-associated protein 1 (1042 aa, ~112 kD) is encoded by the human SIPA1 gene. This protein is localized to the nucleus and… 
National Institutes of Health

Related topics

Related topics

3 relations
SIPA1 geneSignal TransductionSignaling Pathway Gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2022
2022
Suppression of SIPA-1 expression may reduce bladder cancer invasion and metastasis via the downregulation of E-cadherin and ZO-1.
The aim of the present study was to investigate the capacity of signal-induced proliferation-associated protein 1 (SIPA-1) to… 
Review
2020
Review
2020
The role of SIPA1 in the development of cancer and metastases (Review).
Cancer is a leading cause of mortality and the majority of deaths are due to metastases. Many molecules have been implicated in… 
2016
2016
Exploring the substrate specificity and catalytic mechanism of imidazolonepropionase (HutI) from Bacillus subtilis.
Imidazolonepropionase (HutI, EC 3.5.2.7) catalyzes the hydrolytic cleavage of carbon-nitrogen bond in 4-imidazolone-5-propionic… 
2015
2015
The SIPA1 -313A>G polymorphism is associated with prognosis in inoperable non-small cell lung cancer
Polymorphism in signal-induced proliferation-associated 1 (SIPA1) gene may contribute to the development of metastasis in human… 
2015
2015
High SIPA-1 expression in proximal tubules of human kidneys under pathological conditions
SummarySystemic lupus erythematosus (SLE) and clear cell renal cell carcinoma (CC-RCC) are serious disorders and usually fatal… 
2013
2013
Association of SIPA1 545 C > T polymorphism with survival in Chinese women with metastatic breast cancer
It has been demonstrated that single nucleotide polymorphisms (SNPs) of SIPA1 (signal-induced proliferation associated gene 1… 
Review
2011
Review
2011
SIPA1 (signal-induced proliferation-associated 1)
Review on SIPA1 (signal-induced proliferation-associated 1), with data on DNA, on the protein encoded, and where the gene is… 
2009
2009
Association of Sipa1-545(C/T) Polymorphism with Breast Cancer Risk and Tumor Characteristics in Chinese Women
Objective: To investigate the association of the Sipa1-545(C/T) polymorphism with breast cancer risk and clinicopathologic… 
1998
1998
Genomic organization and cloning of the human homologue of murine Sipa-1.
1997
1997
Mitogen-inducible SIPA1 is mapped to the conserved syntenic groups of chromosome 19 in mouse and chromosome 11q13.3 centromeric to BCL1 in human.
Sipa1, previously called Spa1, is transcriptionally induced in the murine lymphoid cells following mitogenic stimulation and… 
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