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SIGLEC16 gene

Known as: SIGLEC16, Siglec-P16, sialic acid binding Ig like lectin 16 (gene/pseudogene) 
 
National Institutes of Health

Papers overview

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2017
2017
Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates
BackgroundSiglecs-11 and -16 are members of the sialic acid recognizing Ig-like lectin family, and expressed in same cells… Expand
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2015
2015
Human-specific evolutionary changes in the biology of siglecs.
Siglecs are a family of sialic acid-recognizing immunoglobulin-like lectins that exhibit multiple human-specific and human… Expand
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2012
2012
Evolution of siglec-11 and siglec-16 genes in hominins.
We previously reported a human-specific gene conversion of SIGLEC11 by an adjacent paralogous pseudogene (SIGLEC16P), generating… Expand
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Highly Cited
2008
Highly Cited
2008
SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.
Sialic acid binding immunoglobulin-like lectins (Siglec) are important components of immune recognition. The organization of… Expand
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