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SIGLEC16 gene

Known as: SIGLEC16, Siglec-P16, sialic acid binding Ig like lectin 16 (gene/pseudogene) 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2008-2017
0120082017

Papers overview

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2018
2018
Examination of signatures of recent positive selection on genes involved in human sialic 1 acid biology
20 Sialic acids are nine carbon sugars ubiquitously found on the surfaces of vertebrate cells 21 and are involved in various… (More)
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2017
2017
Coevolution of Siglec-11 and Siglec-16 via gene conversion in primates
Siglecs-11 and -16 are members of the sialic acid recognizing Ig-like lectin family, and expressed in same cells. Siglec-11… (More)
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2012
2012
Evolution of siglec-11 and siglec-16 genes in hominins.
We previously reported a human-specific gene conversion of SIGLEC11 by an adjacent paralogous pseudogene (SIGLEC16P), generating… (More)
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2008
2008
SIGLEC16 encodes a DAP12-associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non-functional alleles in humans.
Sialic acid binding immunoglobulin-like lectins (Siglec) are important components of immune recognition. The organization of… (More)
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