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SIB 1508Y

Known as: SIB-1508Y 
 
National Institutes of Health

Papers overview

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2008
2008
(S)-(2)-5-ethynyl-3-(1-methyl-2-pyrrolidinyl)pyridine HCl (SIB-1508Y, Altinicline), is a subtype-selective neuronal nicotinic… Expand
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2006
2006
Altinicline (SIB-1508Y), an anti-Parkinson's agent, was prepared in five steps from natural nicotine in 32% overall yield via a… Expand
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2006
2006
  • Neurology
  • 2006
  • Corpus ID: 31720763
This randomized, placebo-controlled, 5-week Phase II trial evaluated the safety and tolerability of SIB-1508Y, a selective α4β2… Expand
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Highly Cited
2000
Highly Cited
2000
Abstract.Rationale: Epidemiological studies of smokers suggest that there is a link between nicotine and depression. Nonetheless… Expand
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2000
2000
Neuronal nicotinic acetylcholine receptors (nAChRs) are a class of ion channels with significant potential as molecular targets… Expand
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Highly Cited
1999
Highly Cited
1999
Monkeys that receive chronic low-dose 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine (MPTP) administration have difficulty… Expand
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Highly Cited
1998
Highly Cited
1998
The potential antiparkinsonian effects of the centrally acting, subtype‐selective neuronal nicotinic acetylcholine receptor… Expand
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Review
1998
Review
1998
This study assessed the relative potencies of levodopa/benserazide and the nicotinic acetylcholine receptor agonist SIB‐1508Y on… Expand
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Review
1998
Review
1998
Neuronal nicotinic acetylcholine receptors (NAChRs) are pentameric ligand-gated ion channel receptors which exist as different… Expand
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