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SHQ1 gene

Known as: SHQ1, S. CEREVISIAE, HOMOLOG OF, SHQ1, H/ACA ribonucleoprotein assembly factor, FLJ10539 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
SHQ1 is an ER stress response gene that facilitates chemotherapeutics-induced apoptosis via sensitizing ER-stress response
SHQ1 was reported to control the biogenesis and assembly of H/ACA ribonucleoprotein particles (RNPs). It was independently… 
2018
2018
SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival
T-acute lymphoblastic leukemia (T-ALL) is an aggressive hematologic malignancy with complicated heterogeneity. Although… 
2017
2017
Inherited SHQ1 mutations impair interaction with NAP57/dyskerin, a major target in dyskeratosis congenita
The inherited bone marrow failure syndrome dyskeratosis congenita (DC) is most frequently caused by mutations in DKC1 (MIM… 
2016
2016
SHQ1 Regulates MYC mRNA Splicing and Promotes T Cell Leukemogenesis
T-acute lymphoblastic leukemias (T-ALLs) are aggressive hematologic tumors resulting from the malignant transformation of T cell… 
Highly Cited
2013
Highly Cited
2013
Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion‐positive prostate cancers
Deletion of 3p13 has been reported from about 20% of prostate cancers. The clinical significance of this alteration and the… 
Review
2013
Review
2013
Regulation of snoRNAs in cancer: close encounters with interferon.
The interferon (IFN) family of cytokines regulates many cellular processes, such as transcription, translation, post… 
Highly Cited
2011
Highly Cited
2011
The H/ACA RNP assembly factor SHQ1 functions as an RNA mimic.
SHQ1 is an essential assembly factor for H/ACA ribonucleoproteins (RNPs) required for ribosome biogenesis, pre-mRNA splicing, and… 
Highly Cited
2009
Highly Cited
2009
SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs.
Assembly of H/ACA RNPs in yeast is aided by at least two accessory factors, Naf1p and Shq1p. Although the function of Naf1p and… 
2009
2009
Structure and Functional Studies of the CS Domain of the Essential H/ACA Ribonucleoparticle Assembly Protein SHQ1*
H/ACA ribonucleoprotein particles are essential for ribosomal RNA and telomerase RNA processing and metabolism. Shq1p has been… 
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