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SHOC2 gene

Known as: KIAA0862, SHOC2 leucine-rich repeat scaffold protein, SUR8 
National Institutes of Health

Papers overview

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2019
2019
Targeted inhibition of the ERK-MAPK pathway, upregulated in a majority of human cancers, has been hindered in the clinic by drug… 
2014
2014
ABSTRACT Scaffold proteins play a critical role in controlling the activity of the extracellular signal-regulated kinase 1/2… 
2012
2012
The use of ultra-precise optical clocks in space (“master clocks”) will allow for a range of new applications in the fields of… 
Highly Cited
2010
Highly Cited
2010
Shoc2/SUR-8 positively regulates Ras/ERK MAP kinase signaling by serving as a scaffold for Ras and Raf. Here, we examined the… 
2010
2010
Activation of Raf1 at the plasma membrane requires not only Ras activation but also an increase in Ca2+ concentration or… 
2010
2010
  • J. Yi, Muyun Chen, R. Xu
  • Developmental dynamics : an official publication…
  • 2010
  • Corpus ID: 19026457
SUR‐8, a conserved leucine‐rich repeats protein, was first identified as a positive regulator of Ras pathway in Caenorhabditis… 
Highly Cited
2009
Highly Cited
2009
N-myristoylation is a common form of co-translational protein fatty acylation resulting from the attachment of myristate to a… 
Highly Cited
1999
Highly Cited
1999
Ras proteins are conserved from yeasts to mammals and implicated in regulation of the actin cytoskeleton. The flightless-1 (fli-1…