SHOC2 gene

Known as: KIAA0862, SHOC2 leucine-rich repeat scaffold protein, SUR8 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2017
024619982017

Papers overview

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2014
2014
Rasopathies are a group of genetic disorders caused by germline mutations in multiple genes of the Extracellular signal-Regulated… (More)
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2014
2014
Noonan-like syndrome with loose anagen hair (NS/LAH; OMIM 607721) is a developmental disorder clinically related to Noonan… (More)
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2014
2014
RASopathies are a group of disorders related to Noonan syndrome that with dysregulated RAS-mitogen-activated protein kinase (MAPK… (More)
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2012
2012
Shoc2 is the putative scaffold protein that interacts with RAS and RAF, and positively regulates signaling to extracellular… (More)
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2011
2011
Sur8/Shoc2 is a scaffold protein that regulates the Ras-extracellular signal-regulated kinase (ERK) pathway. However, the roles… (More)
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2010
2010
Shoc2/SUR-8 positively regulates Ras/ERK MAP kinase signaling by serving as a scaffold for Ras and Raf. Here, we examined the… (More)
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2006
2006
Erbin is a member of the LAP (leucine-rich repeat (LRR) and PDZ domain) family. It inhibits Ras-mediated activation of ERK in… (More)
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2005
2005
Growth hormone (GH) and IGF-I play important roles in wound healing during intestinal injury and inflammation, but there is also… (More)
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1999
1999
Ras proteins are conserved from yeasts to mammals and implicated in regulation of the actin cytoskeleton. The flightless-1 (fli-1… (More)
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Highly Cited
1998
Highly Cited
1998
We describe the identification and characterization of a novel gene, sur-8, that positively regulates Ras-mediated signal… (More)
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