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Hepatitis C virus (HCV) utilizes autophagy to promote its propagation. Here we show the autophagy-mediated suppression of HCV… Expand The aim of our study was to analyze the alterations of some candidate tumor suppressor genes (TSGs) viz. LIMD1, LTF, CDC25A… Expand p63, a member of the p53 family, is transcribed from two different promoters giving rise to two different proteins: TAp63 that… Expand Scotin is a pro-apoptotic mammalian gene, which is induced upon DNA damage or cellular stress in a p53-dependent manner. In this… Expand ALG-2 (apoptosis linked gene 2 product) is a calcium binding protein for which no clear cellular function has been established… Expand Cell death is an essential event in normal life and development, as well as in the pathophysiological processes that lead to… Expand p73, like its homologue, the tumor suppressor p53, is able to induce apoptosis in several cell types. This property is important… Expand p73, like its family member p53, can induce programmed cell death following DNA damage. Here, we report that this mechanism also… Expand p53 is a transcription factor that induces growth arrest or apoptosis in response to cellular stress. To identify new p53… Expand !
CICR occurs after uncaging calcium at apical (red) but not basal (blue) locations.
Most models of intracellular Ca2… Expand