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SFPQ gene

Known as: PSF, polypyrimidine tract binding protein associated, PTB-ASSOCIATED SPLICING FACTOR 
This gene may be involved in both transcriptional regulation and nuclear RNA processing.
National Institutes of Health

Related topics

Related topics

8 relations
PSF-TFE3 Fusion Protein ExpressionPTB-associated splicing factorRNA BindingRNA Splicing
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SFPQ wt Allele

Papers overview

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Highly Cited
2018
Highly Cited
2018
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS
Mutations causing amyotrophic lateral sclerosis (ALS) strongly implicate ubiquitously expressed regulators of RNA processing. To… Expand
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Highly Cited
2015
Highly Cited
2015
The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation
SFPQ, (a.k.a. PSF), is a human tumor suppressor protein that regulates many important functions in the cell nucleus including… Expand
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Highly Cited
2015
Highly Cited
2015
The soil microbial community predicts the importance of plant traits in plant-soil feedback.
Reciprocal interaction between plant and soil (plant-soil feedback, PSF) can determine plant community structure. Understanding… Expand
2015
2015
Arginine methylation and citrullination of splicing factor proline- and glutamine-rich (SFPQ/PSF) regulates its association with mRNA.
Splicing factor proline- and glutamine-rich (SFPQ) also commonly known as polypyrimidine tract-binding protein-associated… Expand
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Highly Cited
2014
Highly Cited
2014
Long noncoding RNA NEAT1-dependent SFPQ relocation from promoter region to paraspeckle mediates IL8 expression upon immune stimuli.
Although thousands of long noncoding RNAs (lncRNAs) are localized in the nucleus, only a few dozen have been functionally… Expand
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Highly Cited
2014
Highly Cited
2014
NEAT1 long noncoding RNA regulates transcription via protein sequestration within subnuclear bodies
Paraspeckles are subnuclear structures formed around NEAT1 lncRNA. Paraspeckles became enlarged after proteasome inhibition… Expand
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Highly Cited
2012
Highly Cited
2012
Tau-Mediated Nuclear Depletion and Cytoplasmic Accumulation of SFPQ in Alzheimer's and Pick's Disease
Tau dysfunction characterizes neurodegenerative diseases such as Alzheimer's disease (AD) and frontotemporal lobar degeneration… Expand
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2011
2011
PSF Suppresses Tau Exon 10 Inclusion by Interacting with a Stem-Loop Structure Downstream of Exon 10
Microtubule binding protein Tau has been implicated in a wide range of neurodegenerative disorders collectively classified as… Expand
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Highly Cited
2011
Highly Cited
2011
The Splicing Factor Proline-Glutamine Rich (SFPQ/PSF) Is Involved in Influenza Virus Transcription
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in… Expand
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Highly Cited
2004
Highly Cited
2004
An Intronic Polypyrimidine-rich Element Downstream of the Donor Site Modulates Cystic Fibrosis Transmembrane Conductance Regulator Exon 9 Alternative Splicing*
Two intronic elements, a polymorphic TGmTn locus at the end of intron 8 and an intronic splicing silencer in intron 9, regulate… Expand
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