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SERPINF1 protein, human

Known as: PEDF protein, human, serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 protein, human 
 
National Institutes of Health

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SERPINF1 gene

Broader (1)

pigment epithelium-derived factor

Papers overview

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2019
2019
Novel anti-angiogenic PEDF-Derived small peptides mitigate, choroidal neovascularization.
Abnormal migration and proliferation of endothelial cells (EC) drive neovascular retinopathies. While anti-VEGF treatment slows… Expand
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2019
2019
Serum pigment epithelium-derived factor: Relationships with cardiovascular events, renal dysfunction, and mortality in the Veterans Affairs Diabetes Trial (VADT) cohort.
BACKGROUND To determine if serum pigment epithelium-derived factor (PEDF) levels predict cardiovascular events, renal dysfunction… Expand
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2014
2014
Synergistic antitumor effect of recombinant adeno-associated virus-mediated pigment epithelium-derived factor with hyperthermia on solid tumor.
Adeno-associated virus (AAV) is an ideal choice for gene delivery; however, its further development has been limited owing to its… Expand
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2014
2014
MP74-06 INDEPENDENT VALIDATION OF A GENOMIC CLASSIFIER IN AN AT RISK POPULATION OF MEN CONSERVATIVELY MANAGED AFTER RADICAL PROSTATECTOMY
RESULTS: The level of PEDF in prostate cancer patients was significantly higher than those in non-cancer patients. Statistical… Expand
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2013
2013
Inhibition of Corneal Neovascularization with the Combination of Bevacizumab and Plasmid Pigment Epithelium-Derived Factor-Synthetic Amphiphile INTeraction-18 (p-PEDF-SAINT-18) Vector in a Rat…
Bevacizumab, a 149-kDa protein, is a recombinant humanized monoclonal antibody to VEGF. PEDF, a 50-kDa glycoprotein, has… Expand
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2010
2010
The pigment epithelial-derived factor gene loaded in PLGA nanoparticles for therapy of colon carcinoma.
Colon carcinoma is one of the common malignant tumors and has high morbidity and mortality in the world. Pigment epithelial… Expand
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2005
2005
Pigment epithelium-derived factor is a pericyte mitogen secreted by microvascular endothelial cells: possible participation of angiotensin II-elicited PEDF downregulation in diabetic retinopathy.
Pigment epithelium-derived factor (PEDF) is a natural extracellular component of the retina with neuronal differentiating… Expand
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2005
2005
Transscleral-RPE permeability of PEDF and ovalbumin proteins: implications for subconjunctival protein delivery.
PURPOSE To investigate the in vitro, ex vivo, and in vivo transscleral-retinal pigment epithelium (RPE) permeability of PEDF and… Expand
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Highly Cited
2002
Highly Cited
2002
Adeno-associated virus type-2 expression of pigmented epithelium-derived factor or Kringles 1–3 of angiostatin reduce retinal neovascularization
Neovascular diseases of the retina include age-related macular degeneration and diabetic retinopathy, and together they comprise… Expand
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