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Abnormal migration and proliferation of endothelial cells (EC) drive neovascular retinopathies. While anti-VEGF treatment slows… Expand BACKGROUND
To determine if serum pigment epithelium-derived factor (PEDF) levels predict cardiovascular events, renal dysfunction… Expand Adeno-associated virus (AAV) is an ideal choice for gene delivery; however, its further development has been limited owing to its… Expand RESULTS: The level of PEDF in prostate cancer patients was significantly higher than those in non-cancer patients. Statistical… Expand Bevacizumab, a 149-kDa protein, is a recombinant humanized monoclonal antibody to VEGF. PEDF, a 50-kDa glycoprotein, has… Expand Colon carcinoma is one of the common malignant tumors and has high morbidity and mortality in the world. Pigment epithelial… Expand Pigment epithelium-derived factor (PEDF) is a natural extracellular component of the retina with neuronal differentiating… Expand PURPOSE
To investigate the in vitro, ex vivo, and in vivo transscleral-retinal pigment epithelium (RPE) permeability of PEDF and… Expand Neovascular diseases of the retina include age-related macular degeneration and diabetic retinopathy, and together they comprise… Expand