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SERINC5 gene

Known as: SERINE INCORPORATOR 5, C5ORF12, CHROMOSOME 5 OPEN READING FRAME 12 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
TIM-mediated inhibition of HIV-1 release is antagonized by Nef but potentiated by SERINC proteins
Significance TIM proteins inhibit release of HIV-1 and other enveloped viruses. However, it is currently unknown whether and how… 
2019
2019
CD4 Expression and Env Conformation Are Critical for HIV-1 Restriction by SERINC5
Restriction factors provide the first line of defense against retrovirus infection by posing several blocks to the viral… 
Highly Cited
2018
Highly Cited
2018
HIV-1 Nef Antagonizes SERINC5 Restriction by Downregulation of SERINC5 via the Endosome/Lysosome System
ABSTRACT The primate lentiviral accessory protein Nef downregulates CD4 and major histocompatibility complex class I (MHC-I) from… 
2018
2018
A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef.
2017
2017
Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction
ABSTRACT Among the five serine incorporator (SERINC) family members, SERINC5 (Ser5) was reported to strongly inhibit HIV-1… 
Highly Cited
2016
Highly Cited
2016
Effect of HIV-1 Env on SERINC5 Antagonism
ABSTRACT SERINC5 is able to restrict HIV-1 infection by drastically impairing the infectivity of viral particles. Studies have… 
2016
2016
Functional Interplay Between Murine Leukemia Virus Glycogag, Serinc5, and Surface Glycoprotein Governs Virus Entry, with Opposite Effects on Gammaretroviral and Ebolavirus Glycoproteins
ABSTRACT Gammaretroviruses, such as murine leukemia viruses (MLVs), encode, in addition to the canonical Gag, Pol, and Env… 
Highly Cited
2016
Highly Cited
2016
The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor
ABSTRACT SERINC3 (serine incorporator 3) and SERINC5 are recently identified host cell inhibitors of HIV-1 particle infectivity… 
Highly Cited
2006
Highly Cited
2006
Expression of tpo mRNA in thyroid tumors: quantitative PCR analysis and correlation with alterations of ret, Braf , ras and pax8 genes.
Immunocytochemistry (ICC) of thyroid peroxidase (TPO) using the monoclonal antibody MoAb47 has been used as malignancy marker on… 
Highly Cited
2005
Highly Cited
2005
Serinc, an Activity-regulated Protein Family, Incorporates Serine into Membrane Lipid Synthesis*
Cell membranes contain various transporter proteins, some of which are responsible for transferring amino acids across membrane… 
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