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SEC61A1 gene

Known as: SEC61A, SEC61 COMPLEX, ALPHA-1 SUBUNIT, SEC61A1 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
Protein transport into the human ER and related diseases, Sec61-channelopathies.
Protein transport into the human endoplasmic reticulum (ER) is relevant to the biogenesis of most soluble and membrane proteins… 
2013
2013
Reorientation of the first signal-anchor sequence during potassium channel biogenesis at the Sec61 complex
The majority of the polytopic proteins that are synthesized at the ER (endoplasmic reticulum) are integrated co-translationally… 
Highly Cited
2012
Highly Cited
2012
Peroxisome Formation Requires the Endoplasmic Reticulum Channel Protein Sec61
In peroxisome formation, models of near‐autonomous peroxisome biogenesis with membrane protein integration directly from the… 
2011
2011
Induction of Endoplasmic Reticulum–Endosome Fusion for Antigen Cross-Presentation Induced by Poly (γ-Glutamic Acid) Nanoparticles
We previously reported that poly (γ-glutamic acid)-based nanoparticles (γ-PGA NPs) are excellent vaccine carriers for inducing… 
2011
2011
This information is current as Dendritic Cell Cross-Priming of T Cells Cell-Mediated Negative Regulation of TRAIL / DR 5 Plays a Critical Role in NK
2010
2010
Structural Studies and the Assembly of the Heptameric Post-translational Translocon Complex*
In Saccharomyces cerevisiae, some of the nascent chains can be post-translationally translocated into the endoplasmic reticulum… 
2010
2010
The mammalian and yeast translocon complexes comprise a characteristic Sec61 channel.
Highly Cited
1998
Highly Cited
1998
Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane.
The evolutionarily conserved Sec61 protein complex mediates the translocation of secretory proteins into the endoplasmic… 
1998
1998
Membrane integration of Sec61alpha: a core component of the endoplasmic reticulum translocation complex.
The Sec61 complex is a central component of the endoplasmic reticulum (ER) translocation site. The complex consists of three… 
1997
1997
Cloning of SEC61 homologues from Schizosaccharomyces pombe and Yarrowia lipolytica reveals the extent of functional conservation within this core component of the ER translocation machinery.
The Sec61 protein is required for protein translocation across the ER membrane in both yeast and mammals and is found in close… 
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