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SDHD gene

Known as: small subunit of cytochrome b, SDH4, succinate dehydrogenase complex subunit D 
This gene plays a role in the localization of succinate dehydrogenase activity.
National Institutes of Health

Related topics

Related topics

5 relations
Cell RespirationHereditary ParagangliomaHereditary Paraganglioma-Pheochromocytoma SyndromeSuccinate Dehydrogenase [Ubiquinone] Cytochrome B Small Subunit, Mitochondrial

Papers overview

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Highly Cited
2013
Highly Cited
2013
Mutations in SDHD lead to autosomal recessive encephalomyopathy and isolated mitochondrial complex II deficiency
Background Defects of the mitochondrial respiratory chain complex II (succinate dehydrogenase (SDH) complex) are extremely rare… 
Highly Cited
2012
Highly Cited
2012
Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: a new association for SDH?
BACKGROUND Mutations in the subunits B, C, and D of succinate dehydrogenase (SDH) mitochondrial complex II have been associated… 
Review
2012
Review
2012
Risk of malignant paraganglioma in SDHB-mutation and SDHD-mutation carriers: a systematic review and meta-analysis
The main objective of this study was to perform a systematic review and meta-analysis on the risk of developing malignant… 
Highly Cited
2010
Highly Cited
2010
Tumor risks and genotype–phenotype–proteotype analysis in 358 patients with germline mutations in SDHB and SDHD
Succinate dehydrogenase B (SDHB) and D (SDHD) subunit gene mutations predispose to adrenal and extraadrenal pheochromocytomas… 
Highly Cited
2005
Highly Cited
2005
Predictors and prevalence of paraganglioma syndrome associated with mutations of the SDHC gene.
CONTEXT Paraganglioma syndrome includes inherited head and neck paragangliomas (HNPs) and adrenal or extra-adrenal… 
Highly Cited
2004
Highly Cited
2004
The Quaternary Structure of the Saccharomyces cerevisiae Succinate Dehydrogenase
Succinate dehydrogenases and fumarate reductases are complex mitochondrial or bacterial respiratory chain proteins with… 
Highly Cited
2004
Highly Cited
2004
Somatic loss of maternal chromosome 11 causes parent-of-origin-dependent inheritance in SDHD-linked paraganglioma and phaeochromocytoma families
Germline mutations in succinate dehydrogenase subunits B, C and D (SDHB, SDHC and SDHD), genes encoding subunits of mitochondrial… 
Highly Cited
2003
Highly Cited
2003
Genetic analysis of mitochondrial complex II subunits SDHD, SDHB and SDHC in paraganglioma and phaeochromocytoma susceptibility
background  Germline mutations in three subunits of mitochondrial complex II (SDHB, SDHC and SDHD) may be associated with… 
Highly Cited
2001
Highly Cited
2001
Germline SDHD mutation in familial phaeochromocytoma
Highly Cited
2001
Highly Cited
2001
Nearly all hereditary paragangliomas in The Netherlands are caused by two founder mutations in the SDHD gene
Hereditary paragangliomas or glomus tumors are usually benign slow‐growing tumors in the head and neck region. The inheritance… 
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