SDHB protein, human

Known as: Ip, SDHB, Ip protein, human 
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (280 aa, ~32 kDa) is encoded by the human SDHB gene. This protein plays a… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1985-2017
0204019852017

Papers overview

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Highly Cited
2011
Highly Cited
2011
Carney-Stratakis syndrome, an inherited condition predisposing affected individuals to gastrointestinal stromal tumor (GIST) and… (More)
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Highly Cited
2011
Highly Cited
2011
Germline succinate dehydrogenase B (SDHB) mutation causes pheochromocytoma/paraganglioma syndrome type 4 (PGL4). PGL4 is… (More)
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Highly Cited
2011
Highly Cited
2011
Mutations in the tumor suppressor genes SDHB, SDHC, and SDHD (or collectively SDHx) cause the inherited paraganglioma syndromes… (More)
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Highly Cited
2010
Highly Cited
2010
Up to 30% of pheochromocytomas and paragangliomas are associated with germline RET, Von Hippel-Lindau (VHL), neurofibromatosis… (More)
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Highly Cited
2010
Highly Cited
2010
The Carney triad (CT) is gastrointestinal stromal tumor (GIST), paraganglioma, and pulmonary chondroma. The GISTs of CT show… (More)
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Highly Cited
2008
Highly Cited
2008
Mitochondrial complex II is a tumor suppressor comprised of four subunits (SdhA, SdhB, SdhC, and SdhD). Mutations in any of these… (More)
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2008
2008
Recently, enzymes of the tricarboxylic acid (TCA) cycle have emerged as novel tumor suppressors. In particular, mutations in the… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Adrenal and extraadrenal paragangliomas are tumors of chromaffin cells that are usually benign but that may also develop… (More)
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Highly Cited
2006
Highly Cited
2006
CONTEXT Activation of the hypoxia-inducible transcription factors HIF-1 and HIF-2 and a HIF-independent defect in developmental… (More)
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Highly Cited
2004
Highly Cited
2004
Hereditary paraganglioma syndrome has recently been shown to be caused by germline heterozygous mutations in three (SDHB, SDHC… (More)
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